PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

Trihelix

Protein Properties

Length: 381aa MW: 43496.6 Da PI: 6.3298

Description

Trihelix family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016434047.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	trihelix	78.3	1.2e-24	76	157	2	86
trihelix 2 WtkqevlaLiearremeerlrrgklkkplWeevskkmrergferspkqCkekwenlnkrykkikegekkrtsessstcpyfdqle 86 W ++e++aLi +rre+++ ++++k++k+lW+++s kmre+gf rsp++C++kw+nl k++kk k++++ + s +++y +++e XP_016434047.1 76 WVQEETRALISLRRELDSLFNTSKSNKHLWDQISLKMREKGFDRSPTMCTDKWRNLLKEFKKAKHNQEP---NGSAKMSYHKEIE 157 ****************************************************************99886...5667888988887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50090	8.711	68	132	IPR017877	Myb-like domain
Gene3D	G3DSA:1.10.10.60	1.6E-4	69	137	IPR009057	Homeodomain-like
SMART	SM00717	6.8E-6	72	134	IPR001005	SANT/Myb domain
CDD	cd12203	1.49E-28	74	139	No hit	No description
Pfam	PF13837	2.6E-19	75	159	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0042802	Molecular Function	identical protein binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 381 aa Download sequence Send to blast
MSDKPPTSIN LYEEQESMDQ HSNHMIIEVA TPNAHLQQPQ QILLPGISGG DTTSSGGEDN 60 NNNNLKLAPK KRAETWVQEE TRALISLRRE LDSLFNTSKS NKHLWDQISL KMREKGFDRS 120 PTMCTDKWRN LLKEFKKAKH NQEPNGSAKM SYHKEIEEIL KARNKNYKNP TLKVDTFMQF 180 SQKGLDDTSI TFGPVEENGR PTLNLERQLD HDGHPLAITA ADAVTASGSP WNWRETPGNG 240 EQSNSAEGRV ISVKWGDYTK RIGIDGTADA IKQAIKSAFR LRTERAFWLE DEQNIVRALD 300 RDMPLGSYTL HVDEGLTIKV CMYEEADHLP VHTEDKTFYT TNDFRDFLSH RGWTCLREYN 360 GYRHVDMLDE LCPGAVYRGI N

Sequence ? help Back to Top

Protein Sequence Length: 381 aa Download sequence Send to blast

MSDKPPTSIN LYEEQESMDQ HSNHMIIEVA TPNAHLQQPQ QILLPGISGG DTTSSGGEDN  60
NNNNLKLAPK KRAETWVQEE TRALISLRRE LDSLFNTSKS NKHLWDQISL KMREKGFDRS  120
PTMCTDKWRN LLKEFKKAKH NQEPNGSAKM SYHKEIEEIL KARNKNYKNP TLKVDTFMQF  180
SQKGLDDTSI TFGPVEENGR PTLNLERQLD HDGHPLAITA ADAVTASGSP WNWRETPGNG  240
EQSNSAEGRV ISVKWGDYTK RIGIDGTADA IKQAIKSAFR LRTERAFWLE DEQNIVRALD  300
RDMPLGSYTL HVDEGLTIKV CMYEEADHLP VHTEDKTFYT TNDFRDFLSH RGWTCLREYN  360
GYRHVDMLDE LCPGAVYRGI N

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2jmw_A	8e-45	70	155	1	86	DNA binding protein GT-1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that binds specifically to the core DNA sequence 5'-GGTTAA-3'. May act as a molecular switch in response to light signals. {ECO:0000269\|PubMed:10437822, ECO:0000269\|PubMed:15044016, ECO:0000269\|PubMed:7866025}.
UniProt	Probable transcription factor that binds specific DNA sequence. {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00640	PBM	Transfer from MDP0000164819	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	S46942	0.0	S46942.1 Box II Factor [tobacco, mRNA Partial, 1506 nt].
GenBank	TOBB2F	0.0	M96432.1 Nicotiana tabacum DNA-binding protein (B2F) gene, 3' end.
GenBank	TOBGT1A	0.0	M93436.2 Nicotiana tabacum DNA-binding protein (GT-1a) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016434047.1	0.0	PREDICTED: trihelix transcription factor GT-4-like
Swissprot	Q9FX53	1e-162	TGT1_ARATH; Trihelix transcription factor GT-1
Swissprot	Q9LU92	1e-162	TGT4_ARATH; Trihelix transcription factor GT-4
TrEMBL	A0A1S3X2C2	0.0	A0A1S3X2C2_TOBAC; trihelix transcription factor GT-4-like
STRING	XP_009784713.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5113	21	36

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G13450.1	1e-162	Trihelix family protein

Publications ? help Back to Top
Le Gourrierec J,Li YF,Zhou DX Transcriptional activation by Arabidopsis GT-1 may be through interaction with TFIIA-TBP-TATA complex. Plant J., 1999. 18(6): p. 663-8 [PMID:10417717] Perisic O,Lam E A tobacco DNA binding protein that interacts with a light-responsive box II element. Plant Cell, 1992. 4(7): p. 831-8 [PMID:1392597]