PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus

Family

WRKY

Protein Properties

Length: 625aa MW: 67519.5 Da PI: 7.9731

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_015870356.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.7	3.3e-30	275	334	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+a+d +++++tYeg+Hnh+ XP_015870356.1 275 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCADDMSILTTTYEGTHNHP 334 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	2.5E-31	260	336	IPR003657	WRKY domain
SuperFamily	SSF118290	4.05E-27	268	336	IPR003657	WRKY domain
PROSITE profile	PS50811	27.875	270	336	IPR003657	WRKY domain
SMART	SM00774	3.0E-36	275	335	IPR003657	WRKY domain
Pfam	PF03106	8.4E-27	276	334	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 625 aa Download sequence Send to blast
MVTNDFLIQL IFVSDHLIVL KIEHGGAKQK ITDDITPSSP KQQDLISCIK QVPSNTTGIE 60 SSSMERDSMV SSSSRKEQDE QLVSTRAEMG EVREENQRLK MYLDRIMKDY QTLQMQFYGI 120 VQHEAKKSTT TSEAISKNHQ QETDQEAELI SLRLGSFSSI TNYYPKKDEK NKASSDHGKE 180 TSSTTDHQVE EGLALGLDCK FEPSKSSGAT DQGPLSNPSP ASSFEETNKE EARETWPPPN 240 KSLTAKRSTD DEVSQQSPAK KARVSVRARC DTPTMNDGCQ WRKYGQKIAK GNPCPRAYYR 300 CTVAPSCPVR KQVQRCADDM SILTTTYEGT HNHPLPISAT AMASTTSAAA SMLLSASTTS 360 SSRSVLNPLS ATTTPADLHG LNFYLSGNSN LKQFYLPNAP LSSTSHPTIT LDLTSNPSSS 420 SLFNKFSPNY PPLYSSSTSL NFGSSESNLM SWSNNGFLSY GTSNSQPYNN SRTQIGNLSL 480 GRQSGTSTST MQQQNNVFQN FLQKNGNNAV PHNPRPQGSI LLPQQALPDS LAAATKAITA 540 DPSFQSALAA ALSTIIGTQG NHGGGGGGSY VQTTKGNNGC ASSYLNRTTS NLQPGNSMFA 600 SSSSLPFSNS KSGSASSGDH REQTN

Sequence ? help Back to Top

Protein Sequence Length: 625 aa Download sequence Send to blast

MVTNDFLIQL IFVSDHLIVL KIEHGGAKQK ITDDITPSSP KQQDLISCIK QVPSNTTGIE  60
SSSMERDSMV SSSSRKEQDE QLVSTRAEMG EVREENQRLK MYLDRIMKDY QTLQMQFYGI  120
VQHEAKKSTT TSEAISKNHQ QETDQEAELI SLRLGSFSSI TNYYPKKDEK NKASSDHGKE  180
TSSTTDHQVE EGLALGLDCK FEPSKSSGAT DQGPLSNPSP ASSFEETNKE EARETWPPPN  240
KSLTAKRSTD DEVSQQSPAK KARVSVRARC DTPTMNDGCQ WRKYGQKIAK GNPCPRAYYR  300
CTVAPSCPVR KQVQRCADDM SILTTTYEGT HNHPLPISAT AMASTTSAAA SMLLSASTTS  360
SSRSVLNPLS ATTTPADLHG LNFYLSGNSN LKQFYLPNAP LSSTSHPTIT LDLTSNPSSS  420
SLFNKFSPNY PPLYSSSTSL NFGSSESNLM SWSNNGFLSY GTSNSQPYNN SRTQIGNLSL  480
GRQSGTSTST MQQQNNVFQN FLQKNGNNAV PHNPRPQGSI LLPQQALPDS LAAATKAITA  540
DPSFQSALAA ALSTIIGTQG NHGGGGGGSY VQTTKGNNGC ASSYLNRTTS NLQPGNSMFA  600
SSSSLPFSNS KSGSASSGDH REQTN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	1e-19	262	336	1	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_015870356.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015870356.1	0.0	probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	1e-118	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A061G420	0.0	A0A061G420_THECC; WRKY DNA-binding protein 72, putative
STRING	XP_009369334.1	0.0	(Pyrus x bretschneideri)
STRING	EOY21754	0.0	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF650	34	134

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	2e-81	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]