PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_015867952.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus
Family E2F/DP
Protein Properties Length: 385aa    MW: 42893.9 Da    PI: 9.8284
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_015867952.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.52.3e-232388171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rk+ksL+ll+++fl+l+++ +   + l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  XP_015867952.1 23 RKQKSLGLLCSNFLSLYNRDDISSIGLDDAASRL---GV--ERRRIYDIVNVLESVGVLARKAKNQYSWKG 88
                    79****************9999************...**..****************************98 PP

2E2F_TDP77.11.7e-24165245171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ +      +++k+RR+YDi+NVL+++nliek     ++k+++rw g
  XP_015867952.1 165 RREKSLALLTQNFVKLFVCSSVDVISLDEAAKLLLGDahnssIMRTKVRRLYDIANVLSSMNLIEKthttdTRKPAFRWLG 245
                     689**************************************999**************************99*******87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.4E-251989IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.06E-152286IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.7E-282388IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.1E-202488IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.103.2E-23161246IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.9E-32165245IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.0E-19167245IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.45E-14167246IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 385 aa     Download sequence    Send to blast
MASLSSASTL PESSSSRHHT YSRKQKSLGL LCSNFLSLYN RDDISSIGLD DAASRLGVER  60
RRIYDIVNVL ESVGVLARKA KNQYSWKGFG AIPRALQQLK DEGLRENFNS LDGSDFAKAS  120
IFNIRVSDDE DDDERFSGPT TGSQTDKSNT SLNLKSSASS KTENRREKSL ALLTQNFVKL  180
FVCSSVDVIS LDEAAKLLLG DAHNSSIMRT KVRRLYDIAN VLSSMNLIEK THTTDTRKPA  240
FRWLGLRGKA ESGSTHNLAL NESRKRSFGA DVTNISFKRN KVDSSIGGQI KHARSAHEVD  300
VSVLEEDSKD TSKSYQFGPF APVTVARVGD SGNSNPRRFH DWESLASTYR PQYQNQALKD  360
LFSHYMEAWK SWYSEVAGKK PIQIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-41222373228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_015867952.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015867952.10.0E2F transcription factor-like E2FE isoform X1
RefseqXP_024924830.10.0E2F transcription factor-like E2FE isoform X1
RefseqXP_024928556.10.0E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-137E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLW9SXR30.0W9SXR3_9ROSA; E2F transcription factor-like E2FE
STRINGXP_010111971.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-139DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]