PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_013618476.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 349aa MW: 39566.2 Da PI: 9.5395 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 70.1 | 2.7e-22 | 11 | 76 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rkeksL++l ++fl+l+++ + + + l+++a +L v +rRRiYD++N+Le+++l++++ kn+++w+g XP_013618476.1 11 RKEKSLGVLVSNFLRLYNRDDVDLIGLDDAAGKL---GV--ERRRIYDVVNILESIGLVARRGKNQYSWRG 76 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 77.8 | 1.1e-24 | 136 | 216 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 +keksL++l+q+f+kl+ +s+++++tl+ ++k+L++ ++++k+RR+YDi+NV++++nliek ++k+++rw g XP_013618476.1 136 KKEKSLWVLAQNFVKLFLCSDDDMITLDGATKALLNVsqdpmNMRTKVRRLYDIANVFSSMNLIEKthipeTKKPAYRWLG 216 69********************************887999******************************99*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.8E-23 | 7 | 77 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.46E-15 | 10 | 74 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 6.0E-26 | 11 | 76 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.4E-18 | 12 | 76 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 5.0E-22 | 134 | 218 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-28 | 136 | 216 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 4.9E-19 | 137 | 216 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 9.07E-12 | 138 | 217 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 349 aa Download sequence Send to blast |
MKSLGRQSYS RKEKSLGVLV SNFLRLYNRD DVDLIGLDDA AGKLGVERRR IYDVVNILES 60 IGLVARRGKN QYSWRGFGQV PPVLSLLKEE GMREKFGIIP CVTNSEMVLY DQVREEPLKL 120 SPDDQENSPS PKLDSKKEKS LWVLAQNFVK LFLCSDDDMI TLDGATKALL NVSQDPMNMR 180 TKVRRLYDIA NVFSSMNLIE KTHIPETKKP AYRWLGAKAI SEARFLAAPA SLCVRIEPRK 240 RAFGTEITNF TTKRAKTDCS IDRKHYESQN TCSVIKQEQC DSKSAVKRPL SPADTSKKTN 300 AGNSNNQSID VLENLSSAHT LQYCNHELTG LLGHYTETWR TWHAEFGRK |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 1e-32 | 10 | 208 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11786543}. | |||||
Uniprot | TISSUE SPECIFICITY: Preferentially expressed in proliferating tissues. Highly expressed in young stalk and young flowers. Lower expression in young leaves and mature flowers. Detected in cotyledonary vascular tissues, the shoot apical meristem, the base of trichomes, the fully developed stomata, the central root cylinder and in the columella of lateral roots but not in the primary root tips or in the leaf epidermal cells. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent regulation of gene expression. Binds specifically the E2 recognition site as a monomer without interacting with DP proteins. May be up-regulating E2FA and down-regulating repressors of cell cycle progression. Promotes cell proliferation and represses cell elongation. Regulated by proteolysis via a ubiquitin-proteasome pathway. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:19937368}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00511 | DAP | Transfer from AT5G14960 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_013618476.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Down-regulated posttranscroptionally by auxin. {ECO:0000269|PubMed:19937368}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AC189232 | 1e-180 | AC189232.1 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrB013N08, complete sequence. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_013618476.1 | 0.0 | PREDICTED: E2F transcription factor-like E2FD isoform X1 | ||||
Swissprot | Q9LFQ9 | 1e-161 | E2FD_ARATH; E2F transcription factor-like E2FD | ||||
TrEMBL | A0A0D3AJ45 | 0.0 | A0A0D3AJ45_BRAOL; Uncharacterized protein | ||||
STRING | Bo2g012280.1 | 0.0 | (Brassica oleracea) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6003 | 25 | 47 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G14960.1 | 1e-163 | DP-E2F-like 2 |