PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_013618175.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
Family Dof
Protein Properties Length: 257aa    MW: 28103.2 Da    PI: 8.655
Description Dof family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_013618175.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-Dof125.61.5e-3952110462
          zf-Dof   4 kalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 
                      al+cprCdstntkfCyynnyslsqPryfCk+C+ryWtkGG+lrn+PvGgg+rknk+s+
  XP_013618175.1  52 LALRCPRCDSTNTKFCYYNNYSLSQPRYFCKSCKRYWTKGGTLRNIPVGGGCRKNKRST 110
                     5789****************************************************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
ProDomPD0074782.0E-3047107IPR003851Zinc finger, Dof-type
PfamPF027016.3E-3454108IPR003851Zinc finger, Dof-type
PROSITE profilePS5088429.30154108IPR003851Zinc finger, Dof-type
PROSITE patternPS0136105692IPR003851Zinc finger, Dof-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0048364Biological Processroot development
GO:0005634Cellular Componentnucleus
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 257 aa     Download sequence    Send to blast
MDQLLHHQDV YGNYNKAREA MRVPCSNPTQ LDHDQKKPSP ATGAARPQPP ELALRCPRCD  60
STNTKFCYYN NYSLSQPRYF CKSCKRYWTK GGTLRNIPVG GGCRKNKRST SSATRSLRTT  120
PEPASHDGKA FSAASFGGFG NNEHIDLSLA FALLNKQPPG SSSQLGFPSE FGSSHQSDME  180
SVFGTSQQKE NTGYVFGNGS SGLEMAMSDP NKVLWGFPWQ VNGEMNMGGG GGGHVDHIDS  240
GREIWTNMNY INSGALM
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: In embryos, present in cells relevant for root initiation and later in vascular tissues. At the globular stage, accumulates in cells adjacent to the hypophysis (extra-embryonic cell specified to become the founder cell of the primary root meristem) (PubMed:20220754). Expressed at preprocambial stages first in wide domains, and later confined to sites of vein development. In young seedlings, first observed in the central region of leaves primordia, and later strongly expressed at sites of midvein, first and second loops, and higher-order veins (PubMed:20563990). {ECO:0000269|PubMed:20220754, ECO:0000269|PubMed:20563990}.
UniprotTISSUE SPECIFICITY: The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) form a short-range concentration gradient that peaks at protophloem sieve elements (PSE) (PubMed:30626969). Accumulates in the stele (PubMed:20563990). {ECO:0000269|PubMed:20563990, ECO:0000269|PubMed:30626969}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). {ECO:0000250|UniProtKB:Q9M2U1, ECO:0000269|PubMed:30626969}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_013618175.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cytokinin in procambium (PubMed:30626969). Induced by the transcription factor MONOPTEROS (MP) in cells relevant for root initiation, and later in vascular tissues and hypophysis (PubMed:20220754). {ECO:0000269|PubMed:20220754, ECO:0000269|PubMed:30626969}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC2347370.0AC234737.1 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrH010D15, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013618175.10.0PREDICTED: dof zinc finger protein DOF5.3-like
SwissprotQ84TE91e-152DOF53_ARATH; Dof zinc finger protein DOF5.3
TrEMBLA0A0D3AKT00.0A0A0D3AKT0_BRAOL; Uncharacterized protein
STRINGBo2g025060.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM61321845
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60200.11e-145TARGET OF MONOPTEROS 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Miyashima S, et al.
    Mobile PEAR transcription factors integrate positional cues to prime cambial growth.
    Nature, 2019. 565(7740): p. 490-494
    [PMID:30626969]