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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_013602159.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 376aa MW: 42387.6 Da PI: 5.5071 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 83.7 | 1.5e-26 | 144 | 209 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+g ++ln +a+ L +v ++RRiYDi+NVLe+++liek+ kn+irwkg XP_013602159.1 144 RYDSSLGLLTKKFVNLIREAEDGSLDLNYCADVL---EV--QKRRIYDITNVLEGVGLIEKTTKNHIRWKG 209 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.4E-28 | 140 | 211 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 7.3E-33 | 144 | 209 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.35E-17 | 144 | 207 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 3.3E-24 | 146 | 209 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 8.50E-41 | 220 | 327 | No hit | No description |
SuperFamily | SSF144074 | 1.33E-28 | 221 | 326 | No hit | No description |
Pfam | PF16421 | 3.3E-27 | 225 | 324 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0000902 | Biological Process | cell morphogenesis | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0042023 | Biological Process | DNA endoreduplication | ||||
GO:0051782 | Biological Process | negative regulation of cell division | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005730 | Cellular Component | nucleolus | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding | ||||
GO:0044212 | Molecular Function | transcription regulatory region DNA binding | ||||
GO:0046982 | Molecular Function | protein heterodimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 376 aa Download sequence Send to blast |
MAATSKSGED PSLSYNHRSP FRFELIHSPS PTDPLQSSSS TPSSTNRPLS VPQQLPNAQS 60 PQIQAHWDES FSPITQKLKS RKNHSISSSS MPGETIDIAK VIVKQESPQD NIKRGTKSKV 120 TKLSKAVKRE GLQLSGPNGS NNCRYDSSLG LLTKKFVNLI REAEDGSLDL NYCADVLEVQ 180 KRRIYDITNV LEGVGLIEKT TKNHIRWKGA DNLGQLELGN QISRLKLEVE SMQSEENRLD 240 DLIRERQEAL RSLEEDEHCK RYMFMTEEDI TSLPCFHNQT LLAIKAPTAS CIEVPDPDEV 300 MSFPQRQYRM VIRSRMGPID VYLLSKHKGD SSMETDESAV DTSSLKIVTS DTDLKTDYWF 360 ESGEEVTLTD LWNNFC |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 4e-24 | 144 | 210 | 7 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:12468727}. | |||||
Uniprot | TISSUE SPECIFICITY: Expressed in meristematic areas, vascular tissues, apical part of the roots, cotyledons, upper region of the hypocotyls, trichomes, young flower buds and pollen grains. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782}. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Involved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00190 | DAP | Transfer from AT1G47870 | Download |
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Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | XP_013602159.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | JN942973 | 0.0 | JN942973.1 Brassica juncea E2F transcription factor (E2Fc) mRNA, partial cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_013602159.1 | 0.0 | PREDICTED: transcription factor E2FC isoform X2 | ||||
Swissprot | Q9FV70 | 0.0 | E2FC_ARATH; Transcription factor E2FC | ||||
TrEMBL | A0A0D3DJW7 | 0.0 | A0A0D3DJW7_BRAOL; Uncharacterized protein | ||||
TrEMBL | A0A3N6S772 | 0.0 | A0A3N6S772_BRACR; Uncharacterized protein | ||||
STRING | Bo8g016640.1 | 0.0 | (Brassica oleracea) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT1G47870.2 | 0.0 | E2F/DP family protein |
Publications ? help Back to Top | |||
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