PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

bHLH

Protein Properties

Length: 209aa MW: 23162.7 Da PI: 8.1989

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011078455.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	37	6.3e-12	43	86	6	54
HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+r+N++++ Lr+++Pk + K++ +iL +++Y+k+L XP_011078455.1 43 LMAERRRRKRLNDRLSMLRSVVPKiS------KMDRTSILGDTIDYMKEL 86 589*******************66......**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.453	37	86	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	6.15E-16	40	104	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.2E-12	43	92	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.3E-9	43	86	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.4E-15	44	98	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.96E-5	44	91	No hit	No description
CDD	cd04873	6.09E-5	135	175	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 209 aa Download sequence Send to blast
MGIGAPCKVE PVPEPPTFNT GFSPESQMKN KGKKLNGQPS KNLMAERRRR KRLNDRLSML 60 RSVVPKISKM DRTSILGDTI DYMKELLDRV SNLQEEMNLG TKELGLFSVF KDVKPSEILV 120 RNSPKVDVER RGSDTKIEIC CAGKPGLLLS TVTTLEASGL EIQHCVISCF NDFAVRASCS 180 EEMKDSAILD SEDIKQALCR NAGYGEGCF

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	45	52	ERRRRKRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269\|PubMed:17088607}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011078455.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_019257273.1	1e-100	PREDICTED: transcription factor bHLH93-like
Swissprot	Q9LSL1	6e-75	BH093_ARATH; Transcription factor bHLH93
TrEMBL	A0A2G9GXR6	1e-108	A0A2G9GXR6_9LAMI; Uncharacterized protein
STRING	XP_009772518.1	7e-99	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA789	24	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65640.1	3e-77	beta HLH protein 93

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sharma N, et al. NO FLOWERING IN SHORT DAY (NFL) is a bHLH transcription factor that promotes flowering specifically under short-day conditions in Arabidopsis. Development, 2016. 143(4): p. 682-90 [PMID:26758694] Chen YS, et al. Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. Plant Mol. Biol., 2017. 93(3): p. 299-311 [PMID:27866313] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]