PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

AP2

Protein Properties

Length: 471aa MW: 52683 Da PI: 6.5129

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011077383.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	54.3	3.3e-17	140	189	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g XP_011077383.1 140 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 189 78*****************......55**********************998 PP
2	AP2	42.1	2.1e-13	232	282	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+++ eAa+a+++a+ k +g XP_011077383.1 232 SKYRGVTLHK-CGRWEARMGQF--L-GKKYIYLGLFDSEIEAARAYDKAAIKCNG 282 89******.7**5553..2.26******99********99776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	2.2E-9	140	189	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.54E-16	140	198	IPR016177	DNA-binding domain
CDD	cd00018	2.91E-11	141	199	No hit	No description
Gene3D	G3DSA:3.30.730.10	3.4E-17	141	198	IPR001471	AP2/ERF domain
SMART	SM00380	1.7E-31	141	203	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.82	141	197	IPR001471	AP2/ERF domain
Pfam	PF00847	5.1E-9	232	282	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.11E-16	232	291	IPR016177	DNA-binding domain
CDD	cd00018	2.92E-25	232	292	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.2E-15	233	290	IPR001471	AP2/ERF domain
SMART	SM00380	4.2E-32	233	296	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	15.514	233	290	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	234	245	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	272	292	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 471 aa Download sequence Send to blast
MLNLNLTIDP SIPIANRAEM ASDEHLILSG DQMEYSGSSN SSIVNVETSS TAGDENSCSN 60 NFVGFDIWKS NGEYEESEKS SCGYVTKEFF PASGEVRPTQ WLDLSEDRRE VAEEMIIAQQ 120 QQQKRQQVKK SRRGPRSRSS QYRGVTFYRR TGRWESHIWD CGKQVYLGGF DTAHAAARAY 180 DRAAIKFRGL DADINFNSSD YEEDLKQMNN LTKEEFVHIL RRQSTGFSRG SSKYRGVTLH 240 KCGRWEARMG QFLGKKYIYL GLFDSEIEAA RAYDKAAIKC NGREAVTNFE PSTYDEELSS 300 EPEIGAGENH DLDLNLGIAP PNRANVQTRD MEMGSFQIQS CSNNPPENTG TKDSASVTVG 360 AQLSHGHVSA SGRPFIWSGV DSSFHLAHKG TTIDKSVEVD PSTNWTWKSP EHFHGNHPLP 420 LFPIAASSGF ATSSFTSSSA AIHELPFNTR SQNHYPPPVA NSNNRSHYRW R

Sequence ? help Back to Top

Protein Sequence Length: 471 aa Download sequence Send to blast

MLNLNLTIDP SIPIANRAEM ASDEHLILSG DQMEYSGSSN SSIVNVETSS TAGDENSCSN  60
NFVGFDIWKS NGEYEESEKS SCGYVTKEFF PASGEVRPTQ WLDLSEDRRE VAEEMIIAQQ  120
QQQKRQQVKK SRRGPRSRSS QYRGVTFYRR TGRWESHIWD CGKQVYLGGF DTAHAAARAY  180
DRAAIKFRGL DADINFNSSD YEEDLKQMNN LTKEEFVHIL RRQSTGFSRG SSKYRGVTLH  240
KCGRWEARMG QFLGKKYIYL GLFDSEIEAA RAYDKAAIKC NGREAVTNFE PSTYDEELSS  300
EPEIGAGENH DLDLNLGIAP PNRANVQTRD MEMGSFQIQS CSNNPPENTG TKDSASVTVG  360
AQLSHGHVSA SGRPFIWSGV DSSFHLAHKG TTIDKSVEVD PSTNWTWKSP EHFHGNHPLP  420
LFPIAASSGF ATSSFTSSSA AIHELPFNTR SQNHYPPPVA NSNNRSHYRW R

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor (By similarity). Involved in spikelet transition (Probable). Together with IDS1, controls synergistically inflorescence architecture and floral meristem establishment via the regulation of spatio-temporal expression of B- and E-function floral organ identity genes in the lodicules and of spikelet meristem genes (PubMed:22003982). Prevents lemma and palea elongation as well as grain growth (PubMed:28066457). Regulates the transition from spikelet meristem to floral meristem, spikelet meristem determinancy and the floral organ development (PubMed:17144896). {ECO:0000250\|UniProtKB:P47927, ECO:0000269\|PubMed:17144896, ECO:0000269\|PubMed:22003982, ECO:0000269\|PubMed:28066457, ECO:0000305\|PubMed:26631749}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011077383.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Target of miR172 microRNA mediated cleavage, particularly during floral organ development. {ECO:0000269\|PubMed:20017947, ECO:0000269\|PubMed:22003982, ECO:0000305\|PubMed:26631749, ECO:0000305\|PubMed:28066457}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011077383.1	0.0	floral homeotic protein APETALA 2
Swissprot	Q8H443	1e-107	AP23_ORYSJ; APETALA2-like protein 3
TrEMBL	A0A2G9GII3	0.0	A0A2G9GII3_9LAMI; Uncharacterized protein
STRING	XP_009606014.1	1e-170	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA591	24	116

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G28550.3	1e-107	related to AP2.7

Publications ? help Back to Top
Lee DY,An G Two AP2 family genes, supernumerary bract (SNB) and Osindeterminate spikelet 1 (OsIDS1), synergistically control inflorescence architecture and floral meristem establishment in rice. Plant J., 2012. 69(3): p. 445-61 [PMID:22003982] Wang L, et al. Coordinated regulation of vegetative and reproductive branching in rice. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(50): p. 15504-9 [PMID:26631749] Dai Z,Wang J,Zhu M,Miao X,Shi Z OsMADS1 Represses microRNA172 in Elongation of Palea/Lemma Development in Rice. Front Plant Sci, 2016. 7: p. 1891 [PMID:28066457]