PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum

Family

bHLH

Protein Properties

Length: 330aa MW: 37387.5 Da PI: 5.4309

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_011073848.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36	1.2e-11	161	204	6	54
HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+r+N++++ Lr+++Pk + K++ +iL +++Y+++L XP_011073848.1 161 LMAERRRRKRLNDRLSMLRSIVPKiS------KMDRTSILGDTIDYMREL 204 589*******************66......*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	3.10E-5	145	209	No hit	No description
SuperFamily	SSF47459	6.02E-15	154	216	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.402	155	204	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.2E-9	161	204	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.3E-12	161	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	7.6E-15	162	215	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	0.00123	256	297	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 330 aa Download sequence Send to blast
MEITQQSLLE ELIMTPKIDN NNWIPFPNEV FPNSWSFAPF DHQTPDQQHL HSPTVANSSL 60 LQLISPAEFG HPCPFLDALT LPEISSFYDM DDVAAMPPVQ EEYVEEMNGE VGFLDNVVNG 120 FFKVETGQVV DTLINMDETG NDIGEKKSRA KKPNGQPSKN LMAERRRRKR LNDRLSMLRS 180 IVPKISKMDR TSILGDTIDY MRELLHKIHR LQEEGMSENL NHIIKLTANS SKDLKPNQVP 240 VRTPPKFDVE RRNKDTRVEV CCTAKPGLLI STLSTLDALG LDIHQCVISC FNDFSFQASC 300 YEVGEHRSFM SSEDVKQALF RNAGYGGRCL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	163	170	ERRRRKRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269\|PubMed:17088607}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_011073848.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011073848.1	0.0	transcription factor bHLH93-like isoform X2
Swissprot	Q9LSL1	3e-77	BH093_ARATH; Transcription factor bHLH93
TrEMBL	A0A2G9HVY4	1e-133	A0A2G9HVY4_9LAMI; Uncharacterized protein
STRING	Migut.H00297.1.p	1e-109	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA789	24	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65640.1	2e-79	beta HLH protein 93

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sharma N, et al. NO FLOWERING IN SHORT DAY (NFL) is a bHLH transcription factor that promotes flowering specifically under short-day conditions in Arabidopsis. Development, 2016. 143(4): p. 682-90 [PMID:26758694] Chen YS, et al. Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. Plant Mol. Biol., 2017. 93(3): p. 299-311 [PMID:27866313] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]