PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Arecales; Arecaceae; Arecoideae; Cocoseae; Elaeidinae; Elaeis

Family

G2-like

Protein Properties

Length: 439aa MW: 48910.1 Da PI: 5.0366

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010936025.1	genome	OG	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	110.9	6.1e-35	209	263	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 k+r+rWtpeLHe+Fveav+qLGGsekAtPk +l+lm+v+gLt++hvkSHLQkYR+ XP_010936025.1 209 KQRMRWTPELHECFVEAVNQLGGSEKATPKGVLKLMNVDGLTIYHVKSHLQKYRT 263 79****************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	14.018	206	266	IPR017930	Myb domain
SuperFamily	SSF46689	8.24E-19	207	263	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	5.9E-33	208	265	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	6.0E-26	209	263	IPR006447	Myb domain, plants
Pfam	PF00249	1.3E-10	211	262	IPR001005	SANT/Myb domain
Pfam	PF14379	1.6E-23	294	340	IPR025756	MYB-CC type transcription factor, LHEQLE-containing domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 439 aa Download sequence Send to blast
MERELSSGPT APLHTPYVKN TGVVESFLSS VSEFSSDVHC TSVPQYERQP VSASYISQPS 60 SSSLSLSSTY SSYSGTCQPS MSNYPKESAE IAWCPDSLQG VLDYSDNVNT MNDQFQSSCV 120 MTSDNLIKQN EWPDLTDLMN GDWDDFLDNR DATEPQPKTS DLHVVYPAAH ASTDLSAHHS 180 QIYQSVRSHS GEQRAVSSLS SSANAAPAKQ RMRWTPELHE CFVEAVNQLG GSEKATPKGV 240 LKLMNVDGLT IYHVKSHLQK YRTARYRPES SEGTSEKNIA PLEEMPSLDL KTGIEITKAL 300 RLQMEVQKRL HEQLEIQRKL QLQIEEQGKY LQMMFEKQCE AGIDKLKAPS NEEDPSSQYS 360 DLTHNVTKDG ISEKDQAETE NCPSGAIMLE ECSRQVGDKQ KILEPDADIR SNMIRSHSSP 420 HKRARSHDAD VSSATSAFY

Sequence ? help Back to Top

Protein Sequence Length: 439 aa Download sequence Send to blast

MERELSSGPT APLHTPYVKN TGVVESFLSS VSEFSSDVHC TSVPQYERQP VSASYISQPS  60
SSSLSLSSTY SSYSGTCQPS MSNYPKESAE IAWCPDSLQG VLDYSDNVNT MNDQFQSSCV  120
MTSDNLIKQN EWPDLTDLMN GDWDDFLDNR DATEPQPKTS DLHVVYPAAH ASTDLSAHHS  180
QIYQSVRSHS GEQRAVSSLS SSANAAPAKQ RMRWTPELHE CFVEAVNQLG GSEKATPKGV  240
LKLMNVDGLT IYHVKSHLQK YRTARYRPES SEGTSEKNIA PLEEMPSLDL KTGIEITKAL  300
RLQMEVQKRL HEQLEIQRKL QLQIEEQGKY LQMMFEKQCE AGIDKLKAPS NEEDPSSQYS  360
DLTHNVTKDG ISEKDQAETE NCPSGAIMLE ECSRQVGDKQ KILEPDADIR SNMIRSHSSP  420
HKRARSHDAD VSSATSAFY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6j4k_A	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j4k_B	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_A	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_C	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_D	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_F	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_H	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
6j5b_J	2e-30	208	267	1	60	Protein PHOSPHATE STARVATION RESPONSE 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in phosphate starvation signaling. Binds to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes. Functionally redundant with PHR1 and PHR3 in regulating Pi starvation response and Pi homeostasis. PHR2 binding to DNA is repressed redundantly by SPX1, SPX2 and SPX4 in a PI-dependent manner. {ECO:0000250\|UniProtKB:Q6Z156}.
UniProt	Transcription factor involved in phosphate starvation signaling (PubMed:18263782, PubMed:26082401). Binds to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation-responsive genes (PubMed:25657119, PubMed:26082401). Functionally redundant with PHR1 and PHR3 in regulating Pi starvation response and Pi homeostasis (PubMed:26082401). Involved in both systematic and local Pi-signaling pathways (PubMed:19704822). Regulates several Pi transporters (PubMed:18263782). Regulates the expression of PT2 (PubMed:20149131). Directly up-regulates SPX1 and SPX2 expression, but PHR2 binding to DNA is repressed redundantly by SPX1 and SPX2 in a PI-dependent manner (PubMed:25271318). The DNA-binding activity is also repressed by SPX4 (PubMed:24692424). Involved in root growth under Pi deprivation (PubMed:18263782). {ECO:0000269\|PubMed:18263782, ECO:0000269\|PubMed:19704822, ECO:0000269\|PubMed:20149131, ECO:0000269\|PubMed:24692424, ECO:0000269\|PubMed:25271318, ECO:0000269\|PubMed:25657119, ECO:0000269\|PubMed:26082401}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by Pi starvation. {ECO:0000269\|PubMed:18263782, ECO:0000269\|PubMed:26082401}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010936023.1	0.0	protein PHOSPHATE STARVATION RESPONSE 2 isoform X1
Refseq	XP_010936024.1	0.0	protein PHOSPHATE STARVATION RESPONSE 2 isoform X1
Refseq	XP_019709490.1	0.0	protein PHOSPHATE STARVATION RESPONSE 2 isoform X1
Refseq	XP_019709491.1	0.0	protein PHOSPHATE STARVATION RESPONSE 2 isoform X1
Swissprot	B8B5N8	1e-102	PHR2_ORYSI; Protein PHOSPHATE STARVATION RESPONSE 2
Swissprot	Q6Z156	1e-102	PHR2_ORYSJ; Protein PHOSPHATE STARVATION RESPONSE 2
TrEMBL	A0A2H3YBK6	0.0	A0A2H3YBK6_PHODC; protein PHOSPHATE STARVATION RESPONSE 2-like isoform X2
TrEMBL	A0A2H3YBR0	0.0	A0A2H3YBR0_PHODC; protein PHOSPHATE STARVATION RESPONSE 2-like isoform X1
STRING	XP_008796363.1	0.0	(Phoenix dactylifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G28610.1	9e-75	phosphate starvation response 1

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Wang C, et al. Involvement of OsSPX1 in phosphate homeostasis in rice. Plant J., 2009. 57(5): p. 895-904 [PMID:19000161] Zhang Q,Wang C,Tian J,Li K,Shou H Identification of rice purple acid phosphatases related to phosphate starvation signalling. Plant Biol (Stuttg), 2011. 13(1): p. 7-15 [PMID:21143719] Wu Z,Ren H,McGrath SP,Wu P,Zhao FJ Investigating the contribution of the phosphate transport pathway to arsenic accumulation in rice. Plant Physiol., 2011. 157(1): p. 498-508 [PMID:21715673] Chen J, et al. OsPHF1 regulates the plasma membrane localization of low- and high-affinity inorganic phosphate transporters and determines inorganic phosphate uptake and translocation in rice. Plant Physiol., 2011. 157(1): p. 269-78 [PMID:21753117] Wang C, et al. Functional characterization of the rice SPX-MFS family reveals a key role of OsSPX-MFS1 in controlling phosphate homeostasis in leaves. New Phytol., 2012. 196(1): p. 139-48 [PMID:22803610] Tian J, et al. Overexpression of OsPAP10a, a root-associated acid phosphatase, increased extracellular organic phosphorus utilization in rice. J Integr Plant Biol, 2012. 54(9): p. 631-9 [PMID:22805094] Shen C, et al. OsARF16, a transcription factor, is required for auxin and phosphate starvation response in rice (Oryza sativa L.). Plant Cell Environ., 2013. 36(3): p. 607-20 [PMID:22913536] Wu P,Shou H,Xu G,Lian X Improvement of phosphorus efficiency in rice on the basis of understanding phosphate signaling and homeostasis. Curr. Opin. Plant Biol., 2013. 16(2): p. 205-12 [PMID:23566853] Wang S, et al. Auxin response factor (OsARF12), a novel regulator for phosphate homeostasis in rice (Oryza sativa). New Phytol., 2014. 201(1): p. 91-103 [PMID:24111723] Shi J, et al. The paralogous SPX3 and SPX5 genes redundantly modulate Pi homeostasis in rice. J. Exp. Bot., 2014. 65(3): p. 859-70 [PMID:24368504] Li S,Wang C,Zhou L,Shou H Oxygen deficit alleviates phosphate overaccumulation toxicity in OsPHR2 overexpression plants. J. Plant Res., 2014. 127(3): p. 433-40 [PMID:24687599] Zhou Z, et al. SPX proteins regulate Pi homeostasis and signaling in different subcellular level. Plant Signal Behav, 2015. 10(9): p. e1061163 [PMID:26224365] Zhang K, et al. Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice. Plant Biotechnol. J., 2016. 14(8): p. 1661-72 [PMID:26806409] Cao Y, et al. Identification and expression analysis of OsLPR family revealed the potential roles of OsLPR3 and 5 in maintaining phosphate homeostasis in rice. BMC Plant Biol., 2016. 16(1): p. 210 [PMID:27716044]