PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

bHLH

Protein Properties

Length: 510aa MW: 56164.2 Da PI: 7.4527

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010552795.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.3	6.5e-09	283	331	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq XP_010552795.1 283 NSHSLAERVRREKISERMKFLQDLVPGC----NKVTGKAVMLDEIINYVQSLQ 331 58***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	5.1E-17	278	348	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.65E-11	278	335	No hit	No description
PROSITE profile	PS50888	15.478	280	330	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.0E-17	281	348	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.3E-6	283	331	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.5E-10	286	336	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 510 aa Download sequence Send to blast
MEKERRLDLV SVICTAGEDS SDYPSLWNNV DRPLETGWNL SNPLPNGDIL LLPNANGFFP 60 HSMAQIPADS GFITRAARFS CYGSGIFGEM LNQPLGVPEP IGLYSQVCGT MQRLQDMPVG 120 TVAKQAHGGQ CSGNELNVGE LPKDASTAVR DGFKNDAGTV IHVGANEEVK VDKPGCSHMS 180 DETRSSGGNG RNELQVGELK SGETPSKCFD RKKRKINSQG YEPNQSSRAL QSGEEPDNNG 240 EKKENYERNT NLSPKKTSGG KQASDPPKEG YIHMRARRGQ ATNSHSLAER VRREKISERM 300 KFLQDLVPGC NKVTGKAVML DEIINYVQSL QRQVEFLSMK LATVNPQLEL NLDGLMAKEA 360 LQLRPGPSSA PPFPQSIMPM AYPPLPHLSQ PGFMEPTLSC MRNPSDVLRQ TVTSPLSPMN 420 EGGFKRPETQ GWECDLQNVV HVCYGTDATP ENQEATGSLP PADMKVEHSD PTIKSPRKTN 480 YQRFSGKKGL NFRDFPEKVI STEQFKRTSR

Sequence ? help Back to Top

Protein Sequence Length: 510 aa Download sequence Send to blast

MEKERRLDLV SVICTAGEDS SDYPSLWNNV DRPLETGWNL SNPLPNGDIL LLPNANGFFP  60
HSMAQIPADS GFITRAARFS CYGSGIFGEM LNQPLGVPEP IGLYSQVCGT MQRLQDMPVG  120
TVAKQAHGGQ CSGNELNVGE LPKDASTAVR DGFKNDAGTV IHVGANEEVK VDKPGCSHMS  180
DETRSSGGNG RNELQVGELK SGETPSKCFD RKKRKINSQG YEPNQSSRAL QSGEEPDNNG  240
EKKENYERNT NLSPKKTSGG KQASDPPKEG YIHMRARRGQ ATNSHSLAER VRREKISERM  300
KFLQDLVPGC NKVTGKAVML DEIINYVQSL QRQVEFLSMK LATVNPQLEL NLDGLMAKEA  360
LQLRPGPSSA PPFPQSIMPM AYPPLPHLSQ PGFMEPTLSC MRNPSDVLRQ TVTSPLSPMN  420
EGGFKRPETQ GWECDLQNVV HVCYGTDATP ENQEATGSLP PADMKVEHSD PTIKSPRKTN  480
YQRFSGKKGL NFRDFPEKVI STEQFKRTSR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. {ECO:0000269\|PubMed:23161888}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010552795.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010552795.1	0.0	PREDICTED: transcription factor bHLH49-like
Swissprot	Q9CAA9	1e-153	BH049_ARATH; Transcription factor bHLH49
TrEMBL	R0GH97	1e-160	R0GH97_9BRAS; Uncharacterized protein
STRING	XP_010552795.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5900	25	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68920.3	1e-157	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Tian C, et al. An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation. Mol. Syst. Biol., 2014. 10: p. 755 [PMID:25358340] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]