PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

bHLH

Protein Properties

Length: 521aa MW: 56349.3 Da PI: 6.9801

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010552794.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.3	6.7e-09	367	415	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq XP_010552794.1 367 NSHSLAERVRREKISERMKFLQDLVPGC----NKVTGKAVMLDEIINYVQSLQ 415 58***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	5.23E-17	362	432	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	4.19E-11	362	419	No hit	No description
PROSITE profile	PS50888	15.478	364	414	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.1E-17	365	432	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.5E-6	367	415	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.5E-10	370	420	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 521 aa Download sequence Send to blast
MDHIGDKDKF AVEKNSSVNN VSCDSVNKPA DWRVCVSNPV SLPTDSYPPG DPMSVGPSSF 60 SQSQMMNSFS KALWHDPSSV QTTGFGSFSV QTDAGSSGVL GVADGNLGSF RNNVDRPLET 120 GWNLSNPLPN GDILLLPNAN GFFPHSMAQI PADSGFITRA ARFSCYGSGI FGEMLNQPLG 180 VPEPIGLYSQ VCGTMQRLQD MPVGTVAKQA HGGQCSGNEL NVGELPKDAS TAVRDGFKND 240 AGTVIHVGAN EEVKVDKPGC SHMSDETRSS GGNGRNELQV GELKSGETPS KCFDRKKRKI 300 NSQGYEPNQS SRALQSGEEP DNNGEKKENY ERNTNLSPKK TSGGKQASDP PKEGYIHMRA 360 RRGQATNSHS LAERVRREKI SERMKFLQDL VPGCNKVTGK AVMLDEIINY VQSLQRQVEF 420 LSMKLATVNP QLELNLDGLM AKEALQLRPG PSSAPPFPQS IMPMAYPPLP HLSQPGFMEP 480 TLSCMRNPSD VLRQTVTSPL SPMNEGGFKR PVYSLALSVS E

Sequence ? help Back to Top

Protein Sequence Length: 521 aa Download sequence Send to blast

MDHIGDKDKF AVEKNSSVNN VSCDSVNKPA DWRVCVSNPV SLPTDSYPPG DPMSVGPSSF  60
SQSQMMNSFS KALWHDPSSV QTTGFGSFSV QTDAGSSGVL GVADGNLGSF RNNVDRPLET  120
GWNLSNPLPN GDILLLPNAN GFFPHSMAQI PADSGFITRA ARFSCYGSGI FGEMLNQPLG  180
VPEPIGLYSQ VCGTMQRLQD MPVGTVAKQA HGGQCSGNEL NVGELPKDAS TAVRDGFKND  240
AGTVIHVGAN EEVKVDKPGC SHMSDETRSS GGNGRNELQV GELKSGETPS KCFDRKKRKI  300
NSQGYEPNQS SRALQSGEEP DNNGEKKENY ERNTNLSPKK TSGGKQASDP PKEGYIHMRA  360
RRGQATNSHS LAERVRREKI SERMKFLQDL VPGCNKVTGK AVMLDEIINY VQSLQRQVEF  420
LSMKLATVNP QLELNLDGLM AKEALQLRPG PSSAPPFPQS IMPMAYPPLP HLSQPGFMEP  480
TLSCMRNPSD VLRQTVTSPL SPMNEGGFKR PVYSLALSVS E

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. {ECO:0000269\|PubMed:23161888}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010552794.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010552544.1	0.0	PREDICTED: transcription factor bHLH49-like isoform X1
Swissprot	Q9CAA9	1e-163	BH049_ARATH; Transcription factor bHLH49
TrEMBL	R0GH97	1e-174	R0GH97_9BRAS; Uncharacterized protein
STRING	XP_010552794.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5900	25	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68920.3	1e-155	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Tian C, et al. An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation. Mol. Syst. Biol., 2014. 10: p. 755 [PMID:25358340] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]