PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

bHLH

Protein Properties

Length: 544aa MW: 58563.4 Da PI: 6.1493

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010551346.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.2	7.1e-09	361	409	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq XP_010551346.1 361 NSHSLAERVRREKISERMKFLQDLVPGC----NKVTGKAVMLDEIINYVQSLQ 409 58***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	4.53E-11	356	413	No hit	No description
SuperFamily	SSF47459	4.45E-17	356	427	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.478	358	408	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.2E-17	359	426	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.8E-6	361	409	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.5E-10	364	414	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 544 aa Download sequence Send to blast
MDHMSDKDKF VVEKSNGVND VSYDSVNTPA DWRVCVSNPV SMPVGSYPPE NPMMSACPSS 60 CSPSQMMDSF GQALWHDPTS VQAIGFSAFS MQTNAGSSNA MGIGNGDRPL ETGWNLPSFL 120 PKGNALLLPN ASGFLPHSMV HFPADSGFIE RAARFSCFNG GNFSDMMNQP VVNPESMGLY 180 SQVGGAMQGL QDMQVGSVYK LAHGGQCPRN ELNASELPND ASTAVKDGFK NDIGIGTHVG 240 SNEEAKVDKP GSSNMSEETR SIGGGRNELQ GGEVNSGETS SKGYDTKKRK RNGQESEPNQ 300 SCRPQHSGEE PENNGAKKQK DEQVTNSPAN MTSGGKQGKQ ASDPTKEGYI HVRARRGQAT 360 NSHSLAERVR REKISERMKF LQDLVPGCNK VTGKAVMLDE IINYVQSLQR QVEFLSMKLA 420 TVNPQLNFNF EGLLAKEALQ LRAGPSSAPS FPQMPMAYPP LPQLSQPGFM QPTLSGMGNP 480 SDILKRTISS PLLPVNGGAF KRPETHGWEG DLQNVVHTSY GVGSPLENQA ATESLPSADM 540 KVEQ

Sequence ? help Back to Top

Protein Sequence Length: 544 aa Download sequence Send to blast

MDHMSDKDKF VVEKSNGVND VSYDSVNTPA DWRVCVSNPV SMPVGSYPPE NPMMSACPSS  60
CSPSQMMDSF GQALWHDPTS VQAIGFSAFS MQTNAGSSNA MGIGNGDRPL ETGWNLPSFL  120
PKGNALLLPN ASGFLPHSMV HFPADSGFIE RAARFSCFNG GNFSDMMNQP VVNPESMGLY  180
SQVGGAMQGL QDMQVGSVYK LAHGGQCPRN ELNASELPND ASTAVKDGFK NDIGIGTHVG  240
SNEEAKVDKP GSSNMSEETR SIGGGRNELQ GGEVNSGETS SKGYDTKKRK RNGQESEPNQ  300
SCRPQHSGEE PENNGAKKQK DEQVTNSPAN MTSGGKQGKQ ASDPTKEGYI HVRARRGQAT  360
NSHSLAERVR REKISERMKF LQDLVPGCNK VTGKAVMLDE IINYVQSLQR QVEFLSMKLA  420
TVNPQLNFNF EGLLAKEALQ LRAGPSSAPS FPQMPMAYPP LPQLSQPGFM QPTLSGMGNP  480
SDILKRTISS PLLPVNGGAF KRPETHGWEG DLQNVVHTSY GVGSPLENQA ATESLPSADM  540
KVEQ

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. {ECO:0000269\|PubMed:23161888}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010551346.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010551346.1	0.0	PREDICTED: transcription factor bHLH49
Swissprot	Q9CAA9	0.0	BH049_ARATH; Transcription factor bHLH49
TrEMBL	R0GH97	0.0	R0GH97_9BRAS; Uncharacterized protein
STRING	XP_010551346.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5900	25	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68920.3	0.0	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Tian C, et al. An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation. Mol. Syst. Biol., 2014. 10: p. 755 [PMID:25358340] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]