PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

MIKC_MADS

Protein Properties

Length: 210aa MW: 23719.6 Da PI: 8.2961

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010534127.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	81.3	6.3e-26	9	58	1	50
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeys 50 kr+en rqvtf+kRr+g+lKKA+ELSvLCdae+ v+ifs++gklye + XP_010534127.1 9 KRVENPVHRQVTFCKRRAGLLKKAKELSVLCDAEIGVLIFSPQGKLYELA 58 799********************************************965 PP
2	K-box	57	8.7e-20	99	180	19	100
K-box 19 qelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100 e++ L++eie+Lq+ +R + G + + + l eL Le++Le + +iRs+K+++ll++i+ l+ ke l+ +nk+Lr k+ee XP_010534127.1 99 DEINMLRQEIEMLQKGIRYMFGGGDGAMGLDELLLLEKHLEYWICQIRSRKMDILLQEIQSLRDKEGVLKAANKYLRDKMEE 180 5899***************************************************************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	8.5E-36	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	29.815	1	61	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	1.31E-27	1	77	IPR002100	Transcription factor, MADS-box
CDD	cd00265	2.83E-39	2	74	No hit	No description
PRINTS	PR00404	3.4E-27	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	3.4E-23	10	56	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.4E-27	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.4E-27	38	59	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS51297	12.458	94	184	IPR002487	Transcription factor, K-box
Pfam	PF01486	2.8E-20	99	178	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010228	Biological Process	vegetative to reproductive phase transition of meristem
GO:0048364	Biological Process	root development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 210 aa Download sequence Send to blast
MARGKVQLKR VENPVHRQVT FCKRRAGLLK KAKELSVLCD AEIGVLIFSP QGKLYELATK 60 GTMEGLIEKY LKCTTASASS ASVSASAAPH EPPNLDPIDE INMLRQEIEM LQKGIRYMFG 120 GGDGAMGLDE LLLLEKHLEY WICQIRSRKM DILLQEIQSL RDKEGVLKAA NKYLRDKMEE 180 NNNSMIAANF APMTTNYSYP LTMPNEIFQY

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5f28_A	1e-15	1	102	1	89	MEF2C
5f28_B	1e-15	1	102	1	89	MEF2C
5f28_C	1e-15	1	102	1	89	MEF2C
5f28_D	1e-15	1	102	1	89	MEF2C
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Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription activator that regulates root development by controlling cell proliferation in root meristem. May mediate responses to auxin in the root. May act as promoter of the flowering transition through up-regulation of SOC, FT and LFY. {ECO:0000269\|PubMed:18203871}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010534127.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin in root phloem. {ECO:0000269\|PubMed:18203871}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010534127.1	1e-156	PREDICTED: agamous-like MADS-box protein AGL12
Swissprot	Q38841	1e-113	AGL12_ARATH; Agamous-like MADS-box protein AGL12
TrEMBL	A0A178W249	1e-112	A0A178W249_ARATH; XAL1
STRING	XP_010534127.1	1e-156	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7052	26	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G71692.1	1e-104	AGAMOUS-like 12

Publications ? help Back to Top
Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox. Plant Physiol., 2004. 136(1): p. 2621-32 [PMID:15375207] Pacheco-Escobedo MA, et al. Longitudinal zonation pattern in Arabidopsis root tip defined by a multiple structural change algorithm. Ann. Bot., 2018. [PMID:27358290] García-Cruz KV, et al. The MADS-box XAANTAL1 increases proliferation at the Arabidopsis root stem-cell niche and participates in transition to differentiation by regulating cell-cycle components. Ann. Bot., 2018. [PMID:27474508]