PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_010520408.1

Organism

Tarenaya hassleriana

Taxonomic ID

28532

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya

Family

C2H2

Protein Properties

Length: 274aa MW: 29284.3 Da PI: 4.9868

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010520408.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.4	0.00024	248	266	1	19
EEETTTTEEESSHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrH 19 ++C+ C+ksF++ L++H XP_010520408.1 248 FSCGSCKKSFNSDNALQSH 266 89****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	9.54E-5	241	270	No hit	No description
Pfam	PF12874	3.8E-4	248	266	No hit	No description
PROSITE profile	PS50157	11.302	248	274	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	250	271	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 274 aa Download sequence Send to blast
MEFWGVEVKA GKPVKVNPDE DALIHISQAS LGEAKDKKGA ESVPLFVKVG DQKLVMGTLS 60 QGNFPQISCD LAFEKEFELS HNWKHGSVYF MGYKSPNFEG QDEEGFYSDS EGSDGEEVPA 120 SVTENGKPGA AVGNAKAAEV KPKAKAKAAE VKKVEKLASK DDDSDEDDES EEEGMGLDDS 180 DDSESEDKVV ETPEKAAPTK KRVNESAPKT PVPSKKAKAD ASTPQKKIEE KKGGKKTPAN 240 GSKSGGQFSC GSCKKSFNSD NALQSHDKAK HAAK

Functional Description ? help Back to Top
Source	Description
UniProt	Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for histone H3 'Lys-9' deacetylation. Involved in rRNA gene silencing in nucleolar dominance. Seems to be implicated in the regulation of genes involved in seeds development. {ECO:0000269\|PubMed:10792817, ECO:0000269\|PubMed:12694598, ECO:0000269\|PubMed:14992728, ECO:0000269\|PubMed:15144374}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010520408.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010520408.1	0.0	PREDICTED: histone deacetylase HDT1-like isoform X2
Swissprot	Q9FVE6	1e-72	HDT1_ARATH; Histone deacetylase HDT1
TrEMBL	A0A178VHN4	3e-73	A0A178VHN4_ARATH; HDT1
STRING	XP_010520407.1	1e-157	(Tarenaya hassleriana)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G44750.1	9e-48	histone deacetylase 3

Publications ? help Back to Top
Song Y,Wu K,Dhaubhadel S,An L,Tian L Arabidopsis DNA methyltransferase AtDNMT2 associates with histone deacetylase AtHD2s activity. Biochem. Biophys. Res. Commun., 2010. 396(2): p. 187-92 [PMID:20331964] Lee K,Park OS,Jung SJ,Seo PJ Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis. J. Plant Physiol., 2016. 191: p. 95-100 [PMID:26724747] Han Z, et al. AtHD2D Gene Plays a Role in Plant Growth, Development, and Response to Abiotic Stresses in Arabidopsis thaliana. Front Plant Sci, 2016. 7: p. 310 [PMID:27066015] Li H, et al. Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number. Plant Cell, 2017. 29(9): p. 2183-2196 [PMID:28855334]