PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

MYB

Protein Properties

Length: 295aa MW: 34085.3 Da PI: 9.3255

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009777823.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	50.8	3.9e-16	88	134	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT eEd ll++ v+++G + W+ Ia+t+ gR +kqc++rw+++l XP_009777823.1 88 KGQWTIEEDRLLIQSVEKFGVRKWSQIAQTLK-GRIGKQCRERWHNHL 134 799**************************9.***********97 PP
2	Myb_DNA-binding	56.3	7.3e-18	142	182	3	45
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 WT+eEd +l+ a+++ G++ W+ Ia++++ gRt++++k++w+ XP_009777823.1 142 LWTEEEDRILISAHAEVGNK-WSEIAKRIP-GRTENSIKNHWN 182 6*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	19.363	83	134	IPR017930	Myb domain
SuperFamily	SSF46689	1.76E-31	87	181	IPR009057	Homeodomain-like
SMART	SM00717	2.1E-13	87	136	IPR001005	SANT/Myb domain
Pfam	PF00249	2.0E-14	88	134	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	3.0E-27	89	141	IPR009057	Homeodomain-like
CDD	cd00167	7.76E-12	91	134	No hit	No description
PROSITE profile	PS51294	26.635	135	189	IPR017930	Myb domain
SMART	SM00717	4.4E-17	139	187	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	4.8E-23	142	188	IPR009057	Homeodomain-like
Pfam	PF00249	1.5E-16	142	182	IPR001005	SANT/Myb domain
CDD	cd00167	1.28E-12	143	185	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010183	Biological Process	pollen tube guidance
GO:0045697	Biological Process	regulation of synergid differentiation
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 295 aa Download sequence Send to blast
MDQDFNFNYE FKPFDQNGTS GSTLVNFNVV PDESSCITTG DNNGNYGKKE IGGRKNKKLV 60 TKSNENSLSS SSMRKLGRGR KKYSKSAKGQ WTIEEDRLLI QSVEKFGVRK WSQIAQTLKG 120 RIGKQCRERW HNHLRPDIKK DLWTEEEDRI LISAHAEVGN KWSEIAKRIP GRTENSIKNH 180 WNATKRRQFS RRKCRTKWPR PSSLLQNYIK SLNFEKGSND TILNNNAHEL CDKGNNIQQL 240 VADYDFSQVP EFGLDDKLFD DLEIPYNELP QLMQAGEVNK EAELMDLISC VNHEI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	4e-44	88	189	27	128	MYB TRANSFORMING PROTEIN
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds to the motif 5'-GTAACNT-3' in the promoter of target genes (e.g. DD11 and DD18) and promotes their expression within synergid cells (e.g. in the filiform apparatus) in ovules (PubMed:16214903, PubMed:17693534, PubMed:18410484, PubMed:17937500). Required for the formation of the filiform apparatus during synergid cell differentiation in the female gametophyte (PubMed:16214903). Involved in pollen tube guidance to the micropyle (PubMed:16214903, PubMed:17937500, PubMed:23093426). {ECO:0000269\|PubMed:16214903, ECO:0000269\|PubMed:17693534, ECO:0000269\|PubMed:17937500, ECO:0000269\|PubMed:18410484, ECO:0000269\|PubMed:23093426}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00442	DAP	Transfer from AT4G18770	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009777823.1	0.0	PREDICTED: transcription factor MYB98-like
Refseq	XP_016433498.1	0.0	PREDICTED: transcription factor MYB98-like
Swissprot	Q9S7L2	6e-76	MYB98_ARATH; Transcription factor MYB98
TrEMBL	A0A1S3X1D3	0.0	A0A1S3X1D3_TOBAC; transcription factor MYB98-like
TrEMBL	A0A1U7WGP3	0.0	A0A1U7WGP3_NICSY; transcription factor MYB98-like
STRING	XP_009777823.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3150	23	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G18770.1	5e-76	myb domain protein 98

Publications ? help Back to Top
Mendes MA, et al. Live and let die: a REM complex promotes fertilization through synergid cell death in Arabidopsis. Development, 2016. 143(15): p. 2780-90 [PMID:27338615]