PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

G2-like

Protein Properties

Length: 311aa MW: 34098.1 Da PI: 6.3176

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009631744.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	95.3	4.7e-30	140	193	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +prl+Wtp+LH+rFv++v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl XP_009631744.1 140 RPRLVWTPQLHKRFVDVVAHL-GIKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 193 59*****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.546	137	196	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	1.6E-30	138	198	IPR009057	Homeodomain-like
SuperFamily	SSF46689	2.87E-19	139	197	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.5E-23	141	193	IPR006447	Myb domain, plants
Pfam	PF00249	5.3E-8	143	192	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0042753	Biological Process	positive regulation of circadian rhythm
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 311 aa Download sequence Send to blast
MGEEVKITDG DAFTGDENRV LEWEEGLPSL EDLTPLSQAL IPPELASAFK ISPEPAKTLS 60 DVNRASESTF SSLRGSGPLQ QLHILSSPET DPTENGLDPR KTRRIDPEML DADSALMRNE 120 NCGGGDDSNN NSASKTLNKR PRLVWTPQLH KRFVDVVAHL GIKNAVPKTI MQLMNVEGLT 180 RENVASHLQK YRLYLKRMQG LSDEGPTSSD HLFASTPVPQ SLQQSGGNGP NSNGHNSSGY 240 NSNGHNGNGH VQMQMPMPMP MMYPPQMVPM PMMGMSGHGH GFHHQYNMGA QQPDWSGNKF 300 GSYHYVAPSD K

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	1e-34	140	196	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00014	PBM	Transfer from AT3G46640	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB219069	0.0	AB219069.1 Nicotiana benthamiana NbPCL1 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009631744.1	0.0	PREDICTED: transcription factor PCL1-like
Swissprot	Q9SNB4	2e-79	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A1S4CQ32	0.0	A0A1S4CQ32_TOBAC; transcription factor PCL1-like
STRING	XP_009631744.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3580	23	43

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	2e-80	G2-like family protein

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]