PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009627739.1
Organism
Nicotiana tomentosiformis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 608aa    MW: 67461 Da    PI: 6.9862
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009627739.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.86.9e-12439485455
                     HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                     +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ +I +Lq
  XP_009627739.1 439 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAHITELQ 485
                     799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.5E-5552240IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.475435484IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474597.98E-18438500IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.67E-13438489No hitNo description
Gene3DG3DSA:4.10.280.102.1E-17439499IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.2E-9439485IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.6E-16441490IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 608 aa     Download sequence    Send to blast
MKIEMGLGNM LWSDEDKAMV AAVLGTKAFD YLMSSSVSAE CSLMAMGNDE NLQNKLSDLV  60
ERPNGANFSW NYAIFWQISR SKSGELVLGW GDGCCREPRE GEGSEITRIL NLRLENEAQQ  120
RMRKRVLEKL HMLFGGTDED NYAFGLDKVT DTEMFFLASM YFSFPRGEGG PGKCFGSGKY  180
VWLSDVMKSS VDYCSRSFLM KSAGMQTIVL IPTDVGVVEL GSVRAISESL ELVQSIKSCF  240
SSFLSLIRAK QAGSVTVVAE KKDGNNFPFS SSFISEQPPN GVPKIFGQNL NSGCTPFREK  300
LVVRKAEDRP LEMYQNGNRA QFLNARNGLR AASWASFSNV KPVNSADPYR PQIPANNVRD  360
FVNGAREEFR TNNFQHQKNA SMQIDFTNSR PVISPAHTVE SEHSDAEASC KEDHAGPVDD  420
KRPRKRGRKP ANGREEPLNH VEAERQRREK LNQRFYALRA VVPNISKMDK ASLLGDAIAH  480
ITELQKKLRD MESESERLGS TSRDANASAS DSPSSETQNR IPDINIEAAN DEVVVRVRCA  540
LETHPASRVI EAFKEARVNV VESKLAAGND AVYHTFVVES SGSEQLTKEK LMAAFSGESN  600
ALRPSPVR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A9e-27482415193Transcription factor MYC3
4rqw_B9e-27482415193Transcription factor MYC3
4rru_A1e-2692365227Transcription factor MYC3
4rs9_A9e-27482415193Transcription factor MYC3
4ywc_A1e-2692365227Transcription factor MYC3
4ywc_B1e-2692365227Transcription factor MYC3
4yz6_A9e-27482415193Transcription factor MYC3
5gnj_A4e-28433498265Transcription factor MYC2
5gnj_B4e-28433498265Transcription factor MYC2
5gnj_E4e-28433498265Transcription factor MYC2
5gnj_F4e-28433498265Transcription factor MYC2
5gnj_G4e-28433498265Transcription factor MYC2
5gnj_I4e-28433498265Transcription factor MYC2
5gnj_M4e-28433498265Transcription factor MYC2
5gnj_N4e-28433498265Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1420428KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009627739.10.0PREDICTED: transcription factor bHLH13-like
RefseqXP_016444111.10.0PREDICTED: transcription factor bHLH13-like isoform X1
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A1S3XVZ20.0A0A1S3XVZ2_TOBAC; transcription factor bHLH13-like isoform X1
STRINGXP_009627739.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.30.0bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]