PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 218aa MW: 23645.2 Da PI: 8.1003

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009621926.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.9	7.9e-05	61	83	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+C++C++ F ++ L H++ H XP_009621926.1 61 YECQYCSREFANSQALGGHQNAH 83 99******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.45E-6	58	88	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.1E-4	59	87	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	12.175	61	88	IPR007087	Zinc finger, C2H2
Pfam	PF13912	1.0E-5	61	85	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	63	83	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 218 aa Download sequence Send to blast
MAELEFQSKH GTYNPTNNGR LKLFGFNMST EEDQEQEVDS TKTSSASPES GSFPASDGRK 60 YECQYCSREF ANSQALGGHQ NAHKKERQQL KRAQIQASRN AYMRNPIISA FASPSHLLTP 120 PGTMVVPASS PSWVYVPRAA PPFHGCVFPT SNSVRGVGNF QYTGGVVESS LASVGPQHVK 180 AHSGRVDVNN GPSLSKLSRV DIGPNFDDPF GLDLQLSL

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin and cytokinin. Acts upstream of GIS, GIS2, ZFP8, and the trichome initiation factors GL1 and GL3. Binds the promoter region of GIS and GIS2, which may be direct targets of GIS3. {ECO:0000269\|PubMed:25640859}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009621926.1	1e-163	PREDICTED: zinc finger protein 6-like
Refseq	XP_016489116.1	1e-163	PREDICTED: zinc finger protein 6-like
Swissprot	Q9C9H1	9e-57	GIS3_ARATH; Zinc finger protein GIS3
TrEMBL	A0A1S4BJQ1	1e-161	A0A1S4BJQ1_TOBAC; zinc finger protein 6-like
STRING	XP_009621926.1	1e-162	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2994	14	19

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G06650.1	4e-14	C2H2 family protein

Publications ? help Back to Top
Sun L, et al. GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis. New Phytol., 2015. 206(1): p. 220-30 [PMID:25640859]