PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

AP2

Protein Properties

Length: 335aa MW: 37972.8 Da PI: 7.3712

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009621695.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	49.5	1.1e-15	54	113	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng...kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d ++n k+ ++++lg ++ +e Aa a++ a++k++g XP_009621695.1 54 SIYRGVTRHRWTGRYEAHLWDkNCWNEtqsKKgRQVYLGAYDDEEAAAHAYDLAALKYWG 113 57*****************999977877557***********************98 PP
2	AP2	49.9	8e-16	156	207	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV +++ +grW+A+I + g +k+ +lg++ t eeAa a++ a+ + +g XP_009621695.1 156 SRYRGVARHHHNGRWEARIGRvF---G-NKYLYLGTYATQEEAAMAYDMAAIEHRG 207 79**99******99966...3.6*********************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	7.77E-11	54	123	No hit	No description
Pfam	PF00847	6.9E-12	54	113	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.55E-17	54	123	IPR016177	DNA-binding domain
SMART	SM00380	2.4E-27	55	127	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.4E-16	55	122	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	20.31	55	121	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.3E-6	56	67	IPR001471	AP2/ERF domain
CDD	cd00018	1.79E-23	156	217	No hit	No description
Pfam	PF00847	1.3E-11	156	207	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.18E-17	156	217	IPR016177	DNA-binding domain
SMART	SM00380	3.1E-26	157	221	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.7E-18	157	216	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.952	157	215	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.3E-6	197	217	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 335 aa Download sequence Send to blast
MAKTSKAYQK NTSYTNSSEK NNSNSGSSSD HAISKGKRKR KAVVSRDSPP QRSSIYRGVT 60 RHRWTGRYEA HLWDKNCWNE TQSKKGRQVY LGAYDDEEAA AHAYDLAALK YWGQDTILNF 120 PVSTYEKELM EMEGQSREEY IGSLRRKSSG FSRGVSRYRG VARHHHNGRW EARIGRVFGN 180 KYLYLGTYAT QEEAAMAYDM AAIEHRGPNA VTNFDLSRYI KCNPQPKPNP NSTDLNTIPN 240 TKEEIDISFT HQQHEQQQSS NSVGTSAPPP HAVGGTAASS AVDCPETPPE PDRPRRCFPD 300 DIQTYFDCQD SSIFVEEHDI IFGDLDSFVL PMFEY

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009621695.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor At1g16060
Refseq	XP_016495796.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor At1g16060 isoform X1
Swissprot	Q94AN4	1e-119	AP2L1_ARATH; AP2-like ethylene-responsive transcription factor At1g16060
TrEMBL	A0A1S4C3P5	0.0	A0A1S4C3P5_TOBAC; AP2-like ethylene-responsive transcription factor At1g16060 isoform X1
STRING	XP_009621695.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1815	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G16060.1	1e-107	ARIA-interacting double AP2 domain protein

Publications ? help Back to Top
Todd J,Post-Beittenmiller D,Jaworski JG KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana. Plant J., 1999. 17(2): p. 119-30 [PMID:10074711] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]