PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009620662.1

Organism

Nicotiana tomentosiformis

Taxonomic ID

4098

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 514aa MW: 57389.9 Da PI: 6.5041

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009620662.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21	8.6e-07	263	284	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H XP_009620662.1 263 FCTICGKGFKRDANLRMHMRGH 284 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.29E-5	260	287	No hit	No description
SMART	SM00355	0.0026	262	284	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.03	262	289	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	8.2E-6	263	313	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	264	284	IPR007087	Zinc finger, C2H2
SMART	SM00355	62	311	344	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	25	349	371	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 514 aa Download sequence Send to blast
MDPDDSLSED PWTKSSSAGN ELLKIVPSDN HSFTNFNLHA QKWEGSSYLD QQTRIEQQFS 60 GFTQPKHTYQ MDQHGNQMNE NHDSTRTKDW DPSTLLNNLS FLEQKIHQLQ ELVHLIVGRR 120 GQTGLQGNDL IVQQQQLITA DLTSIIVQLV STAGSLLPTM KRTLSSVSPA ASQLVQFGGV 180 TVPSATCTNG GGLPCNDGGV TKVEDQSNHV DQLRDCGIEQ NHAVDGHESK DEDEAEEEEN 240 LPPGSYEILQ LEKEEILAPH THFCTICGKG FKRDANLRMH MRGHGDEYKT PAALAKPHKE 300 PSSEPTLIKR YSCPYVGCKR NKEHKKFQPL KTILCVKNHY KRTHCEKAYT CSRCNIKKFS 360 VIADLKTHEK HCGKDKWLCS CGTTFSRKDK LFGHIALFQG HTPAVPLDET KGSAGTSDRG 420 QTSEVTMKAR QEDFKVNASH GNEFQNPRDI KSAADDPGSY FSPLNFDTSN LNGFQEFPRP 480 PFDESDSSFS FLLSGSCEYP PHKAAKYMSS SELE

Sequence ? help Back to Top

Protein Sequence Length: 514 aa Download sequence Send to blast

MDPDDSLSED PWTKSSSAGN ELLKIVPSDN HSFTNFNLHA QKWEGSSYLD QQTRIEQQFS  60
GFTQPKHTYQ MDQHGNQMNE NHDSTRTKDW DPSTLLNNLS FLEQKIHQLQ ELVHLIVGRR  120
GQTGLQGNDL IVQQQQLITA DLTSIIVQLV STAGSLLPTM KRTLSSVSPA ASQLVQFGGV  180
TVPSATCTNG GGLPCNDGGV TKVEDQSNHV DQLRDCGIEQ NHAVDGHESK DEDEAEEEEN  240
LPPGSYEILQ LEKEEILAPH THFCTICGKG FKRDANLRMH MRGHGDEYKT PAALAKPHKE  300
PSSEPTLIKR YSCPYVGCKR NKEHKKFQPL KTILCVKNHY KRTHCEKAYT CSRCNIKKFS  360
VIADLKTHEK HCGKDKWLCS CGTTFSRKDK LFGHIALFQG HTPAVPLDET KGSAGTSDRG  420
QTSEVTMKAR QEDFKVNASH GNEFQNPRDI KSAADDPGSY FSPLNFDTSN LNGFQEFPRP  480
PFDESDSSFS FLLSGSCEYP PHKAAKYMSS SELE

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB811781	0.0	AB811781.1 Nicotiana tabacum NtSTOP1 mRNA for STOP1-like protein, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009620662.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Refseq	XP_016487627.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A1S4BFG4	0.0	A0A1S4BFG4_TOBAC; protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
STRING	XP_009620662.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4754	24	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	1e-171	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]