PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 298aa MW: 33215.3 Da PI: 6.517

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009619639.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	55.8	8e-18	128	182	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++keq Lee F+++++++ +++ L+k+l+L rqV vWFqNrRa+ k XP_009619639.1 128 RKKLRLSKEQAALLEETFKEHNTLNPKQKLALSKQLNLRPRQVEVWFQNRRARTK 182 788899***********************************************98 PP
2	HD-ZIP_I/II	125.1	3.3e-40	128	217	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlskeq++lLEe+F+e+++L+p++K +l+++L+l+prqv+vWFqnrRARtk+kq+E+d+e+L+r++++l+een+rL+kev+eLr +l XP_009619639.1 128 RKKLRLSKEQAALLEETFKEHNTLNPKQKLALSKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLRRCCENLTEENRRLQKEVTELR-AL 217 69*************************************************************************************9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51257	5	1	19	No hit	No description
Pfam	PF04618	4.5E-16	4	104	IPR006712	HD-ZIP protein, N-terminal
SuperFamily	SSF46689	8.13E-18	121	185	IPR009057	Homeodomain-like
PROSITE profile	PS50071	16.876	124	184	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	5.7E-17	124	187	IPR009057	Homeodomain-like
SMART	SM00389	2.3E-14	126	188	IPR001356	Homeobox domain
Pfam	PF00046	3.2E-15	128	182	IPR001356	Homeobox domain
CDD	cd00086	8.36E-15	128	185	No hit	No description
PROSITE pattern	PS00027	0	159	182	IPR017970	Homeobox, conserved site
Pfam	PF02183	8.7E-11	184	218	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	2.1E-25	184	227	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 298 aa Download sequence Send to blast
MGGEKEDGLG LSLSLGMSCP QNNLKNNDFI SSSTPPFLLP FLHNHQISAE RNEEAKESIR 60 GEIDMNQPAR MIESCDEELE DEGLIMVSSP NNSTVSSVSG KRSHDREDNE GERPTSSLED 120 DGGDAAARKK LRLSKEQAAL LEETFKEHNT LNPKQKLALS KQLNLRPRQV EVWFQNRRAR 180 TKLKQTEVDC EYLRRCCENL TEENRRLQKE VTELRALKLS PQMYMNMTPP TTLTMCPQCE 240 RVAVSSSSSS AASSSVTGAG VSRSNHPVGA LHQPPVPLNK PWAAIFSPKT LDVQRTQL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	176	184	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT013613	1e-158	BT013613.1 Lycopersicon esculentum clone 132414F, mRNA sequence.
GenBank	X91212	1e-158	X91212.1 L.esculentum mRNA for HD-ZIP protein.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009619639.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT3-like
Refseq	XP_016462220.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT3-like
Swissprot	P46602	2e-80	HAT3_ARATH; Homeobox-leucine zipper protein HAT3
TrEMBL	A0A1S3ZCP5	0.0	A0A1S3ZCP5_TOBAC; homeobox-leucine zipper protein HAT3-like
STRING	XP_009619639.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60390.1	1e-74	homeobox-leucine zipper protein 3

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Caggiano MP, et al. Cell type boundaries organize plant development. Elife, 2018. [PMID:28895530]