PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 238aa MW: 26575.2 Da PI: 9.8037

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009612669.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	57.5	2.3e-18	100	154	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ ++tk q Lee F+++++++ +++++LA+kl++ rqV vWFqNrRa+ k XP_009612669.1 100 RKKLRLTKVQSALLEESFKQHSTLNPKQKQHLARKLNVRPRQVEVWFQNRRARTK 154 678899***********************************************98 PP
2	HD-ZIP_I/II	119.8	1.5e-38	100	189	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rl+k q++lLEesF+++++L+p++K++lar+L+++prqv+vWFqnrRARtk+kq+E+d+e+Lk+++++l++en++L ke +eL+ +l XP_009612669.1 100 RKKLRLTKVQSALLEESFKQHSTLNPKQKQHLARKLNVRPRQVEVWFQNRRARTKLKQTEVDCEFLKKCCESLTDENRKLYKELQELK-AL 189 69*************************************************************************************9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	2.42E-18	86	157	IPR009057	Homeodomain-like
PROSITE profile	PS50071	16.52	96	156	IPR001356	Homeobox domain
SMART	SM00389	1.6E-14	98	160	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	8.2E-17	100	154	IPR009057	Homeodomain-like
CDD	cd00086	1.65E-15	100	157	No hit	No description
Pfam	PF00046	8.3E-16	100	154	IPR001356	Homeobox domain
PROSITE pattern	PS00027	0	131	154	IPR017970	Homeobox, conserved site
SMART	SM00340	2.4E-22	156	199	IPR003106	Leucine zipper, homeobox-associated
Pfam	PF02183	4.7E-9	156	190	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 238 aa Download sequence Send to blast
MGFDDICGTG LALKLGFSST ANNQRSRKPP ADLLGKEGSL SFEPSLTLSL PKDQSADHLS 60 SSTYSNASVK RKRDISTEVE RVLSSRVSDE DLDDHVSNGR KKLRLTKVQS ALLEESFKQH 120 STLNPKQKQH LARKLNVRPR QVEVWFQNRR ARTKLKQTEV DCEFLKKCCE SLTDENRKLY 180 KELQELKALK LAQPLYRQLP AAATLAVCPS CERVAGAGEN APAKPHFYSP FTSPSATC

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	148	156	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009612669.1	1e-175	PREDICTED: homeobox-leucine zipper protein HAT22-like
Refseq	XP_016455411.1	1e-175	PREDICTED: homeobox-leucine zipper protein HAT22-like
Swissprot	P46604	8e-83	HAT22_ARATH; Homeobox-leucine zipper protein HAT22
TrEMBL	A0A1S3YT41	1e-174	A0A1S3YT41_TOBAC; homeobox-leucine zipper protein HAT22-like
STRING	XP_009612669.1	1e-175	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA290	24	186

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37790.1	1e-72	HD-ZIP family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Liu T,Longhurst AD,Talavera-Rauh F,Hokin SA,Barton MK The Arabidopsis transcription factor ABIG1 relays ABA signaled growth inhibition and drought induced senescence. Elife, 2017. [PMID:27697148] Song L, et al. A transcription factor hierarchy defines an environmental stress response network. Science, 2017. [PMID:27811239]