PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 500aa MW: 53687.3 Da PI: 8.1808

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009612198.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	58	80	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H XP_009612198.1 58 FVCEICNKGFQRDQNLQLHRRGH 80 89*******************88 PP
2	zf-C2H2	16.7	2e-05	134	156	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC+ C+k + +s+ k H++t+ XP_009612198.1 134 FKCERCTKKYAVQSDWKAHMKTC 156 89*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.02E-7	57	80	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-5	57	80	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.017	58	80	IPR015880	Zinc finger, C2H2-like
Pfam	PF12171	8.0E-5	58	80	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.949	58	80	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	60	80	IPR007087	Zinc finger, C2H2
SMART	SM00355	220	99	129	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.6E-5	122	155	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	2.02E-7	129	155	No hit	No description
SMART	SM00355	63	134	154	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 500 aa Download sequence Send to blast
MAEMENSSSM TVAGSSLEET ITQQNFPVKK KRNLPGNPDP EAEVIALSPK TLMATNRFVC 60 EICNKGFQRD QNLQLHRRGH NLPWKLRQRT SKEVKKRVYV CPEAMCVHHD PSRALGDLTG 120 IKKHFCRKHG EKKFKCERCT KKYAVQSDWK AHMKTCGTRE YRCDCGTLFS RRDSFITHRA 180 FCDALAQESA RAQPMGITNT EENLKVDEAV TSSSSPPPQP LTPSTGVLSP VLSIQSSELP 240 TDNQNQAGVQ LQAAQGTTPV STTTVTATTI STTASITGPG SSKVFASVFP PSSTLAGHPH 300 SSYSDILCAI GPEQISPIEP MSLSLSSSFY LSANDGSTLF QDHTGHSQHY GSTTQSVLSA 360 TALLQKAAQM GATSSNNSFL RGLGLAMSST SASDNISRVK LENNVELPGL GIQLPSNGPS 420 GRWTDLMMGP SHESMMFGNK PPTLDFLGLG NDANATSSNG FSALLSSMDG GFGVATTSYG 480 GVATRGEAWD GHSDRKPSML

Sequence ? help Back to Top

Protein Sequence Length: 500 aa Download sequence Send to blast

MAEMENSSSM TVAGSSLEET ITQQNFPVKK KRNLPGNPDP EAEVIALSPK TLMATNRFVC  60
EICNKGFQRD QNLQLHRRGH NLPWKLRQRT SKEVKKRVYV CPEAMCVHHD PSRALGDLTG  120
IKKHFCRKHG EKKFKCERCT KKYAVQSDWK AHMKTCGTRE YRCDCGTLFS RRDSFITHRA  180
FCDALAQESA RAQPMGITNT EENLKVDEAV TSSSSPPPQP LTPSTGVLSP VLSIQSSELP  240
TDNQNQAGVQ LQAAQGTTPV STTTVTATTI STTASITGPG SSKVFASVFP PSSTLAGHPH  300
SSYSDILCAI GPEQISPIEP MSLSLSSSFY LSANDGSTLF QDHTGHSQHY GSTTQSVLSA  360
TALLQKAAQM GATSSNNSFL RGLGLAMSST SASDNISRVK LENNVELPGL GIQLPSNGPS  420
GRWTDLMMGP SHESMMFGNK PPTLDFLGLG NDANATSSNG FSALLSSMDG GFGVATTSYG  480
GVATRGEAWD GHSDRKPSML

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	3e-34	130	199	3	72	Zinc finger protein JACKDAW
5b3h_F	3e-34	130	199	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation (PubMed:21571950). Acts as a positive regulator of phytochrome and/or gibberellin action (PubMed:21571950, PubMed:25035403). {ECO:0000269\|PubMed:21571950, ECO:0000269\|PubMed:25035403}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009612196.1	0.0	PREDICTED: protein indeterminate-domain 2-like isoform X1
Swissprot	Q9LVQ7	1e-133	IDD1_ARATH; Zinc finger protein ENHYDROUS
TrEMBL	A0A1S4D7A7	0.0	A0A1S4D7A7_TOBAC; protein indeterminate-domain 2-like isoform X1
STRING	XP_009612196.1	0.0	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-113	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]