PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

AP2

Protein Properties

Length: 466aa MW: 51581.9 Da PI: 8.3889

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009611308.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	53.3	7e-17	146	195	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g XP_009611308.1 146 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHTAARAYDRAAIKFRG 195 78*****************......55**********************997 PP
2	AP2	38	4.2e-12	238	288	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+++GV+ +k grW+A+ + +k+ +lg f+++ eAa+a+++a+ k +g XP_009611308.1 238 SKFRGVTLHK-CGRWEARMGQF--L-GKKYMYLGLFDSEVEAARAYDKAAIKTNG 288 79******.7**5553..2.26******99********98766 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	6.9E-9	146	195	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	8.5E-16	146	204	IPR016177	DNA-binding domain
CDD	cd00018	1.67E-23	147	205	No hit	No description
SMART	SM00380	3.6E-32	147	209	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.8E-17	147	203	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.662	147	203	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.19E-16	238	297	IPR016177	DNA-binding domain
Pfam	PF00847	2.8E-7	238	286	IPR001471	AP2/ERF domain
CDD	cd00018	1.21E-23	238	298	No hit	No description
PROSITE profile	PS51032	15.264	239	296	IPR001471	AP2/ERF domain
SMART	SM00380	8.9E-30	239	302	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	6.8E-15	239	296	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.6E-5	240	251	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.6E-5	278	298	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010228	Biological Process	vegetative to reproductive phase transition of meristem
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 466 aa Download sequence Send to blast
MLDLNVNVIY DENYIVDEKL PEGSVADHES GTSNSSSLRN AEATSSAGGD DDTCSTRAGN 60 LFAFNFDILK FGGVDTTSRS NKFVTRQLFP VHDGELNRPG QTDRVNFSSG RSGFGDERTV 120 LQQQQQSQQE KPQVKKSRRG PRSRSSQYRG VTFYRRTGRW ESHIWDCGKQ VYLGGFDTAH 180 TAARAYDRAA IKFRGVDADI NFSISDYEED MKQMKDLGKE EFVHLLRRHS NGFSRGSSKF 240 RGVTLHKCGR WEARMGQFLG KKYMYLGLFD SEVEAARAYD KAAIKTNGRE AVTNFEPSAY 300 EGETISEPQG RQHDLDLNLG MSTSSSKEND KLGGSYYHPY DMQDATKSKM DKPGPVIVGS 360 SHLKGLPMTS KQAHLWSGAS SNFSPTYEGR ASDKRKDIGS SQGPSNWALQ MPSQVDTAPV 420 SMFYTAASSG FLTPATAFIT SSASPVAPST NASQYYYQFS PHVPPP

Sequence ? help Back to Top

Protein Sequence Length: 466 aa Download sequence Send to blast

MLDLNVNVIY DENYIVDEKL PEGSVADHES GTSNSSSLRN AEATSSAGGD DDTCSTRAGN  60
LFAFNFDILK FGGVDTTSRS NKFVTRQLFP VHDGELNRPG QTDRVNFSSG RSGFGDERTV  120
LQQQQQSQQE KPQVKKSRRG PRSRSSQYRG VTFYRRTGRW ESHIWDCGKQ VYLGGFDTAH  180
TAARAYDRAA IKFRGVDADI NFSISDYEED MKQMKDLGKE EFVHLLRRHS NGFSRGSSKF  240
RGVTLHKCGR WEARMGQFLG KKYMYLGLFD SEVEAARAYD KAAIKTNGRE AVTNFEPSAY  300
EGETISEPQG RQHDLDLNLG MSTSSSKEND KLGGSYYHPY DMQDATKSKM DKPGPVIVGS  360
SHLKGLPMTS KQAHLWSGAS SNFSPTYEGR ASDKRKDIGS SQGPSNWALQ MPSQVDTAPV  420
SMFYTAASSG FLTPATAFIT SSASPVAPST NASQYYYQFS PHVPPP

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay. {ECO:0000250, ECO:0000269\|PubMed:14555699}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00615	PBM	Transfer from AT2G28550	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by miR172a-2/EAT. {ECO:0000269\|PubMed:14555699}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ586954	0.0	HQ586954.1 Solanum lycopersicum AP2 transcription factor SlAP2e mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009611308.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor TOE3 isoform X1
Refseq	XP_009611309.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor TOE3 isoform X1
Refseq	XP_009611311.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor TOE3 isoform X1
Refseq	XP_018629183.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor TOE3 isoform X1
Swissprot	Q9SK03	1e-104	RAP27_ARATH; Ethylene-responsive transcription factor RAP2-7
TrEMBL	A0A1S3WYP7	0.0	A0A1S3WYP7_TOBAC; AP2-like ethylene-responsive transcription factor TOE3 isoform X1
STRING	XP_009611308.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA591	24	116

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G28550.3	1e-118	related to AP2.7