PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 216aa MW: 25272.6 Da PI: 5.8441

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009605338.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	59.4	5.8e-19	55	108	4	57
-SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHHC CS Homeobox 4 RttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakekk 57 ++++++eq++ Le+ F +++++ +e++ +LA++lgL+ qV vWFqNrRa++k+ XP_009605338.1 55 KRKLSEEQVNLLEQSFGNEHKLETERKDKLASELGLDPHQVAVWFQNRRARYKN 108 45899***********************************************95 PP
2	HD-ZIP_I/II	115.3	3.5e-37	54	145	2	93
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 +kr+ls+eqv+lLE+sF +e+kLe+erK +la+eLgl+p+qvavWFqnrRAR+k+k+lE++y++Lk++yd e++rLe+ev +++e+l+e XP_009605338.1 54 RKRKLSEEQVNLLEQSFGNEHKLETERKDKLASELGLDPHQVAVWFQNRRARYKNKKLEQEYSKLKTQYDIAIVEKCRLENEVIKMKEQLSE 145 8***************************************************************************************9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	16.795	49	109	IPR001356	Homeobox domain
SMART	SM00389	3.8E-17	52	113	IPR001356	Homeobox domain
SuperFamily	SSF46689	3.76E-17	54	117	IPR009057	Homeodomain-like
CDD	cd00086	7.24E-14	54	110	No hit	No description
Pfam	PF00046	4.8E-16	55	108	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	2.3E-19	56	116	IPR009057	Homeodomain-like
PRINTS	PR00031	1.7E-5	80	89	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	84	107	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.7E-5	89	105	IPR000047	Helix-turn-helix motif

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 216 aa Download sequence Send to blast
MKNSMTHQLD DQMVLISQYY PDIYTQLVSE PGEAKQQRRR KKSKGEGSRS GVMRKRKLSE 60 EQVNLLEQSF GNEHKLETER KDKLASELGL DPHQVAVWFQ NRRARYKNKK LEQEYSKLKT 120 QYDIAIVEKC RLENEVIKMK EQLSEAENEI QKLLLERNCD GVSSNSPIST SSFTMDQPPF 180 LGEFGMEGML MDNLFFIAEN TYNYQEGLEW VNPVYI

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	37	55	RRRKKSKGEGSRSGVMRKR
2	39	56	RKKSKGEGSRSGVMRKRK

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA) and by salt stress. {ECO:0000269\|PubMed:16055682}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009605338.1	1e-161	PREDICTED: homeobox-leucine zipper protein ATHB-40-like
Swissprot	O23208	1e-69	ATB40_ARATH; Homeobox-leucine zipper protein ATHB-40
TrEMBL	A0A1S4DI66	1e-158	A0A1S4DI66_TOBAC; homeobox-leucine zipper protein ATHB-40-like
STRING	XP_009605338.1	1e-160	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1289	24	80

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36740.1	1e-64	homeobox protein 40

Publications ? help Back to Top
González-Grandío E, et al. Abscisic acid signaling is controlled by a BRANCHED1/HD-ZIP I cascade in Arabidopsis axillary buds. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(2): p. E245-E254 [PMID:28028241]