PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009602360.1

Common Name

sAn1

Organism

Nicotiana tomentosiformis

Taxonomic ID

4098

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 681aa MW: 75440.3 Da PI: 4.989

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009602360.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	43.8	4.8e-14	481	526	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h +ErrRR+++N++f Lr+l+P +K++Ka+iL ++eY+k+L XP_009602360.1 481 NHVLAERRRREKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQL 526 7999********************8.....8***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	3.4E-50	10	187	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.688	477	526	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.24E-15	481	531	No hit	No description
Pfam	PF00010	1.3E-11	481	526	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.44E-18	481	541	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.9E-19	481	543	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.9E-18	483	532	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010026	Biological Process	trichome differentiation
GO:0010214	Biological Process	seed coat development
GO:2000029	Biological Process	regulation of proanthocyanidin biosynthetic process
GO:0000976	Molecular Function	transcription regulatory region sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 681 aa Download sequence Send to blast
MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCSQQGVLVW RDGYYNGAIK TRKTVQPMEV 60 SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI 120 GLPGKAYSKK HHIWIMCANE VDSKVFCRAI LAKTVVCIPL LDGVLELGTT ERVQEDIGFI 180 NHVKSFFTEQ QQPQPPKPAL SEHSTSNSTT FSEPHFYSGN TPPSGNADIA QQDGGAAGEE 240 DEEEEEEEDD EAELDSDSIA IQSEVGGAAN PIAAEASELM QLDMSEAIRL GSPDDGSNNM 300 DSDFHLVGAG NTADYQRQPD SFKAETAISW AHFQDLQHLP GGSSYEELSQ EDTHYSQTVS 360 TILEHFSNRS SKFSSTTMGC ISHDSAQSAF TLCPSTTVDC SPNPAHCRRR HDDSLLDGGG 420 ASPSSQWLLK SILFTVPFLH TKYQSEASPK SVDVATVDSS STASRFRKGC SITSQEEPSG 480 NHVLAERRRR EKLNERFIIL RSLVPFVTKM DKASILGDTI EYVKQLHKKV QDLEARARHT 540 EQSKDAVTKD QKSGTATVKV LQGRGKRRMN TVEAGNFGGR QAKMTAFPLS TTEDEEVVQV 600 EVSIIESDAL LELRCPYKEG LLLDVMQMLR ELKVEVVAIQ SSLNNGIFLA ELRAKVKENI 660 YGRKASIVEV KKSIHQIIPR D

Sequence ? help Back to Top

Protein Sequence Length: 681 aa Download sequence Send to blast

MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCSQQGVLVW RDGYYNGAIK TRKTVQPMEV  60
SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI  120
GLPGKAYSKK HHIWIMCANE VDSKVFCRAI LAKTVVCIPL LDGVLELGTT ERVQEDIGFI  180
NHVKSFFTEQ QQPQPPKPAL SEHSTSNSTT FSEPHFYSGN TPPSGNADIA QQDGGAAGEE  240
DEEEEEEEDD EAELDSDSIA IQSEVGGAAN PIAAEASELM QLDMSEAIRL GSPDDGSNNM  300
DSDFHLVGAG NTADYQRQPD SFKAETAISW AHFQDLQHLP GGSSYEELSQ EDTHYSQTVS  360
TILEHFSNRS SKFSSTTMGC ISHDSAQSAF TLCPSTTVDC SPNPAHCRRR HDDSLLDGGG  420
ASPSSQWLLK SILFTVPFLH TKYQSEASPK SVDVATVDSS STASRFRKGC SITSQEEPSG  480
NHVLAERRRR EKLNERFIIL RSLVPFVTKM DKASILGDTI EYVKQLHKKV QDLEARARHT  540
EQSKDAVTKD QKSGTATVKV LQGRGKRRMN TVEAGNFGGR QAKMTAFPLS TTEDEEVVQV  600
EVSIIESDAL LELRCPYKEG LLLDVMQMLR ELKVEVVAIQ SSLNNGIFLA ELRAKVKENI  660
YGRKASIVEV KKSIHQIIPR D

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	1e-18	10	187	9	192	Transcription factor MYC3
4rqw_B	1e-18	10	187	9	192	Transcription factor MYC3
4rs9_A	1e-18	10	187	9	192	Transcription factor MYC3
4yz6_A	1e-18	10	187	9	192	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	485	490	ERRRRE
2	486	491	RRRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the control of flavonoid pigmentation. {ECO:0000269\|PubMed:20949001}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ589211	0.0	HQ589211.1 Nicotiana tomentosiformis anthocyanin 1-like protein (sAn1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009602360.1	0.0	PREDICTED: basic helix-loop-helix protein A isoform X2
Swissprot	E3SXU4	0.0	BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBL	A0A1S3ZY28	0.0	A0A1S3ZY28_TOBAC; basic helix-loop-helix protein A-like isoform X1
STRING	XP_009602346.1	0.0	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	6e-90	bHLH family protein

Link Out ? help Back to Top
Entrez Gene	104097487

Publications ? help Back to Top
Hellens RP, et al. Identification of Mendel's white flower character. PLoS ONE, 2010. 5(10): p. e13230 [PMID:20949001] Bai Y, et al. Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active. Planta, 2011. 234(2): p. 363-75 [PMID:21484270]