PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 247aa MW: 27143.1 Da PI: 6.1544

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009600791.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	10.9	0.0015	95	117	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C+ C + F ++ L H++ H XP_009600791.1 95 FSCNFCRRKFYSSQALGGHQNAH 117 89*****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	3.72E-6	93	122	No hit	No description
PROSITE profile	PS50157	11.198	95	122	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	97	117	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 247 aa Download sequence Send to blast
MKPPNFNLES EDESEVSSCQ LGSNIYVQET CPGPSKDSST NSCLTNSFNL QQDSKPVTLD 60 LTLGFNSSDP ELNANGETSD EVVPHPPTAA LSRIFSCNFC RRKFYSSQAL GGHQNAHKRE 120 RTLAKRAMRM GMLSDRYASL ASLPLHGAAF RSLGVEAHAS MHQRVSYQET LTHASRGGAR 180 FEQGYFGMPV FVEDDEVEMF WPGSFRQVEG IGGNQRFNSG QGSNINFVAV APQTRTDPSL 240 PDLNLKL

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. {ECO:0000269\|PubMed:24808098}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975443	0.0	HG975443.1 Solanum pennellii chromosome ch04, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009600791.1	0.0	PREDICTED: zinc finger protein 4-like isoform X1
Refseq	XP_009600792.1	0.0	PREDICTED: zinc finger protein 4-like isoform X1
Refseq	XP_009600793.1	0.0	PREDICTED: zinc finger protein 4-like isoform X1
Swissprot	Q39263	6e-47	ZFP4_ARATH; Zinc finger protein 4
TrEMBL	A0A1S4AWW7	1e-168	A0A1S4AWW7_TOBAC; zinc finger protein 4-like isoform X1
TrEMBL	A0A1U7YNA2	1e-168	A0A1U7YNA2_NICSY; zinc finger protein 4-like isoform X1
STRING	XP_009600791.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1283	23	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G66140.1	3e-49	zinc finger protein 4

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]