PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 347aa MW: 39078.1 Da PI: 6.7909

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009594706.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	103.3	1.4e-32	189	246	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+WrKYGqK+vk+s fpr+YYrCtsa+C+vkk+ver+ +dp++v++tYeg+H+h+ XP_009594706.1 189 EDGYRWRKYGQKTVKNSSFPRNYYRCTSASCNVKKRVERCFNDPSIVVTTYEGKHTHP 246 8********************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.7E-35	173	248	IPR003657	WRKY domain
SuperFamily	SSF118290	3.01E-29	180	248	IPR003657	WRKY domain
PROSITE profile	PS50811	30.871	183	248	IPR003657	WRKY domain
SMART	SM00774	3.4E-38	188	247	IPR003657	WRKY domain
Pfam	PF03106	1.3E-25	189	246	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009624	Biological Process	response to nematode
GO:0009733	Biological Process	response to auxin
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 347 aa Download sequence Send to blast
MESYKDITIK MEDPMSYFDN FPVISNSFTG LVSDYNFAVE GKNNSINSSL GFMELLGVQD 60 FCSTSVFDVN SITTNLDQLL PKEEKYHIEP AVSISEEVKP SPAAESKKKI TVAAHESSNN 120 ILNTPSTPNS SSISSETNEG HAQDAEGEVA EEQITKTKLQ LKAKKTVNQK KQREPRIAFM 180 TKSEVDFLED GYRWRKYGQK TVKNSSFPRN YYRCTSASCN VKKRVERCFN DPSIVVTTYE 240 GKHTHPSPMN MNMNMINMPR PTLFPTRVFP LPAPTATFPL QMPFHINQSA QPHFNDLTTP 300 LASNLDHAAL VAHGRRFCSA PPSVEIMRDQ GLLQDLMSSR VVEEDYR

Sequence ? help Back to Top

Protein Sequence Length: 347 aa Download sequence Send to blast

MESYKDITIK MEDPMSYFDN FPVISNSFTG LVSDYNFAVE GKNNSINSSL GFMELLGVQD  60
FCSTSVFDVN SITTNLDQLL PKEEKYHIEP AVSISEEVKP SPAAESKKKI TVAAHESSNN  120
ILNTPSTPNS SSISSETNEG HAQDAEGEVA EEQITKTKLQ LKAKKTVNQK KQREPRIAFM  180
TKSEVDFLED GYRWRKYGQK TVKNSSFPRN YYRCTSASCN VKKRVERCFN DPSIVVTTYE  240
GKHTHPSPMN MNMNMINMPR PTLFPTRVFP LPAPTATFPL QMPFHINQSA QPHFNDLTTP  300
LASNLDHAAL VAHGRRFCSA PPSVEIMRDQ GLLQDLMSSR VVEEDYR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	2e-26	181	248	10	77	Probable WRKY transcription factor 4
2lex_A	2e-26	181	248	10	77	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00069	PBM	Transfer from AT2G47260	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU056916	1e-95	EU056916.1 Solanum tuberosum WRKY transcription factor 4 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009594706.1	0.0	PREDICTED: probable WRKY transcription factor 23
Swissprot	O22900	1e-48	WRK23_ARATH; WRKY transcription factor 23
TrEMBL	A0A1S3YLD2	0.0	A0A1S3YLD2_TOBAC; probable WRKY transcription factor 23
STRING	XP_009594706.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1309	24	79

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47260.1	2e-44	WRKY DNA-binding protein 23

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guo D,Qin G EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signal Behav, 2016. 11(3): p. e1150404 [PMID:26914912] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885]