PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 274aa MW: 31115.1 Da PI: 8.2101

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009590779.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	58	1.6e-18	115	169	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ ++tkeq +Lee F+++++++ +++ LAk+lgL rqV vWFqNrRa+ k XP_009590779.1 115 RKKLRLTKEQSAVLEENFKEHSTLNPKQKLALAKRLGLRARQVEVWFQNRRARTK 169 678899***********************************************98 PP
2	HD-ZIP_I/II	121.5	4.2e-39	115	204	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rl+keq+++LEe+F+e+++L+p++K +la++Lgl++rqv+vWFqnrRARtk+kq+E d+++Lkr++++l+een+rL+kev+eLr +l XP_009590779.1 115 RKKLRLTKEQSAVLEENFKEHSTLNPKQKLALAKRLGLRARQVEVWFQNRRARTKLKQTELDCDFLKRCVENLTEENRRLQKEVQELR-AL 204 69*************************************************************************************9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	8.7E-23	2	89	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	3.8E-17	90	168	IPR009057	Homeodomain-like
SuperFamily	SSF46689	3.8E-18	104	172	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.038	111	171	IPR001356	Homeobox domain
SMART	SM00389	5.2E-15	113	175	IPR001356	Homeobox domain
Pfam	PF00046	4.2E-16	115	169	IPR001356	Homeobox domain
CDD	cd00086	7.65E-14	115	172	No hit	No description
PRINTS	PR00031	3.3E-5	142	151	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	146	169	IPR017970	Homeobox, conserved site
PRINTS	PR00031	3.3E-5	151	167	IPR000047	Helix-turn-helix motif
Gene3D	G3DSA:1.20.5.170	4.4E-4	169	203	No hit	No description
Pfam	PF02183	2.6E-9	171	205	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	5.2E-25	171	214	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 274 aa Download sequence Send to blast
MEDLGLSLSL SFPQNRTVTN LIRKTSWTDN SFPSSDRNSE TCRVETKTFL KGIDVNRLPE 60 TADAEEEAGV SSPNSTISSV SGNKRNDREA NCEEHDMERA CSRGISDEED GETCRKKLRL 120 TKEQSAVLEE NFKEHSTLNP KQKLALAKRL GLRARQVEVW FQNRRARTKL KQTELDCDFL 180 KRCVENLTEE NRRLQKEVQE LRALKLSPQF YMQMTPPTTL TMCPSCERVA SGPTSTPVNL 240 RLGPPQQLNL WATTPISQGQ FGQMDSHPTL ARQK

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	163	171	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975518	5e-60	HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009590779.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT4-like
Swissprot	P46600	3e-96	HAT1_ARATH; Homeobox-leucine zipper protein HAT1
TrEMBL	A0A1S4C9T7	0.0	A0A1S4C9T7_TOBAC; homeobox-leucine zipper protein HAT4-like
STRING	XP_009590779.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G16780.1	3e-85	homeobox protein 2

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Tan W, et al. Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genet., 2018. 14(4): p. e1007336 [PMID:29659577]