PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WOX

Protein Properties

Length: 309aa MW: 34896.3 Da PI: 7.0383

Description

WOX family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009587430.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62.8	5e-20	49	110	2	57
T--SS--HHHHHHHHHHHHH..SSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 2 rkRttftkeqleeLeelFek..nrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 ++R+t+t++q+++L++l+++ r p+ae+++++++kl +++ ++V++WFqN++a+e++ XP_009587430.1 49 STRWTPTTDQIRILKDLYYNngVRSPTAEQIQRISAKLrqygKIEGKNVFYWFQNHKARERQ 110 58***************8678***********************************97 PP
2	Wus_type_Homeobox	114.1	6.9e-37	48	112	2	65
Wus_type_Homeobox 2 artRWtPtpeQikiLeelyk.sGlrtPnkeeiqritaeLeeyGkiedkNVfyWFQNrkaRerqkq 65 ++tRWtPt++Qi+iL++ly+ +G+r+P++e+iqri+a+L++yGkie+kNVfyWFQN+kaRerqk+ XP_009587430.1 48 SSTRWTPTTDQIRILKDLYYnNGVRSPTAEQIQRISAKLRQYGKIEGKNVFYWFQNHKARERQKK 112 789*************9779***************************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	1.1E-7	33	110	IPR009057	Homeodomain-like
SuperFamily	SSF46689	8.13E-12	34	112	IPR009057	Homeodomain-like
PROSITE profile	PS50071	10.527	45	111	IPR001356	Homeobox domain
SMART	SM00389	4.9E-6	47	115	IPR001356	Homeobox domain
CDD	cd00086	5.91E-7	50	112	No hit	No description
Pfam	PF00046	2.3E-17	50	110	IPR001356	Homeobox domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010492	Biological Process	maintenance of shoot apical meristem identity
GO:0080166	Biological Process	stomium development
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 309 aa Download sequence Send to blast
MEAAQQQNQQ HYLHQQHLSI GQVANNIEDG VGGNSSKNNS SSFMCRQSST RWTPTTDQIR 60 ILKDLYYNNG VRSPTAEQIQ RISAKLRQYG KIEGKNVFYW FQNHKARERQ KKRLIAAAAT 120 DNNNNIPMQM RGVWRSADDP IHHKYNNTTG IHCPSASSHG VLAVGQNGNY GYGTVAMEKS 180 FRDCSISPGG NSNGSMGHQN ITWVGVDPYT SHQAYPFLEK TKHFDETLDD YEELQQEEEN 240 YQRASALETL PLFPMHEENI SSFCNIKHES SGGFYTEWYR SDDHNLAAAA RASLELSLNS 300 FIGRSPNSP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that plays a central role during developmental processes such as early embryogenesis and flowering, probably by regulating expression of specific genes. Required to specify stem cell identity in meristems, such as shoot apical meristem (SAM). Acts in parallel with HAM. {ECO:0000269\|PubMed:12208843}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00265	DAP	Transfer from AT2G17950	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JQ686923	0.0	JQ686923.1 Nicotiana tabacum cultivar SR1 WUSCHEL (WUS) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009587430.1	0.0	PREDICTED: protein WUSCHEL
Refseq	XP_016493082.1	0.0	PREDICTED: protein WUSCHEL-like
Swissprot	Q8LL11	1e-156	WUS_PETHY; Protein WUSCHEL
TrEMBL	A0A1S4BW28	0.0	A0A1S4BW28_TOBAC; protein WUSCHEL-like
STRING	XP_009587430.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA7604	23	31

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G17950.1	8e-41	WOX family protein

Publications ? help Back to Top
Stuurman J,Jäggi F,Kuhlemeier C Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells. Genes Dev., 2002. 16(17): p. 2213-8 [PMID:12208843]