PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 250aa MW: 28717.7 Da PI: 4.7722

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009587238.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60.1	3.6e-19	43	95	4	56
-SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 4 RttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 ++f++eq++ Le++Fe++ ++ +++ +LA++lgL+ rqV +WFqN+Ra++k XP_009587238.1 43 TRRFSDEQIKSLETMFENETKLEPRKKLQLARELGLQPRQVAIWFQNKRARWK 95 469*************************************************9 PP
2	HD-ZIP_I/II	122.6	2e-39	42	133	2	93
HD-ZIP_I/II 2 kkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 + rr+s+eq+k+LE++Fe+e+kLep++K +lareLglqprqva+WFqn+RAR+k+kqlE+dy+ Lk+++d+l+++ ++L+ke+++L +l++ XP_009587238.1 42 NTRRFSDEQIKSLETMFENETKLEPRKKLQLARELGLQPRQVAIWFQNKRARWKSKQLERDYNILKSNFDHLASQYNSLKKENQSLLLQLQK 133 569***********************************************************************************999886 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	7.35E-19	21	99	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.313	37	97	IPR001356	Homeobox domain
SMART	SM00389	1.8E-16	40	101	IPR001356	Homeobox domain
Pfam	PF00046	1.5E-16	43	95	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	1.1E-19	43	104	IPR009057	Homeodomain-like
CDD	cd00086	1.98E-15	44	98	No hit	No description
PRINTS	PR00031	1.0E-5	68	77	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	72	95	IPR017970	Homeobox, conserved site
PRINTS	PR00031	1.0E-5	77	93	IPR000047	Helix-turn-helix motif
Pfam	PF02183	2.0E-15	97	139	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0009738	Biological Process	abscisic acid-activated signaling pathway
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 250 aa Download sequence Send to blast
MFDGGEFSCT SSAAALNSAE CFSSSSFSSL PSSKKKKVNN KNTRRFSDEQ IKSLETMFEN 60 ETKLEPRKKL QLARELGLQP RQVAIWFQNK RARWKSKQLE RDYNILKSNF DHLASQYNSL 120 KKENQSLLLQ LQKLNDLMQK ERGQYCSIGF DQESYNRDDN TIKNKEMEGK PSLSFDLSEH 180 GVNGVISDDD SSIKADYFGL DEESDHLLKM VEAGDSSLTS PENWGSLEDD GLLDQQPNSS 240 NYDQWWDFWS

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription activator that may act as growth regulators in response to water deficit. {ECO:0000269\|PubMed:15604708, ECO:0000269\|PubMed:8771791}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00320	DAP	Transfer from AT2G46680	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By water deficit, by abscisic acid (ABA) and by salt stress. {ECO:0000269\|PubMed:16055682, ECO:0000269\|PubMed:8771791}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GQ859155	0.0	GQ859155.1 Nicotiana benthamiana HB1 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009587238.1	0.0	PREDICTED: homeobox-leucine zipper protein ATHB-12-like
Swissprot	P46897	7e-69	ATHB7_ARATH; Homeobox-leucine zipper protein ATHB-7
TrEMBL	A0A1S3Y4I8	1e-180	A0A1S3Y4I8_TOBAC; homeobox-leucine zipper protein ATHB-12-like
STRING	XP_009587238.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2041	23	63

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G46680.1	2e-59	homeobox 7

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zhou SF, et al. Membrane-associated transcription factor peptidase, site-2 protease, antagonizes ABA signaling in Arabidopsis. New Phytol., 2015. 208(1): p. 188-97 [PMID:25919792]