PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

AP2

Protein Properties

Length: 333aa MW: 37500 Da PI: 9.7414

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009150822.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	46.5	9.2e-15	72	131	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + g ++ ++++lg ++ +++Aa+a++ a++k++g XP_009150822.1 72 SIYRGVTRHRWTGRYEAHLWDnSCRrEGqaRKgRQVYLGGYDKEDKAARAYDLAALKYWG 131 57*****************666664478446******99***********98 PP
2	AP2	49.9	7.7e-16	176	225	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GV++++++grW A+I + +k +lg+f t+eeAa+a++ a+ k++g XP_009150822.1 176 YRGVTRHHQQGRWQARIGRVAG---NKDLYLGTFATEEEAAEAYDIAAIKFRG 225 9*************988532...5**********************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	6.67E-21	72	141	No hit	No description
SuperFamily	SSF54171	1.24E-16	72	140	IPR016177	DNA-binding domain
Pfam	PF00847	1.1E-11	72	131	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	18.755	73	139	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.6E-15	73	139	IPR001471	AP2/ERF domain
SMART	SM00380	1.5E-26	73	145	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.0E-6	74	85	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	5.49E-18	174	234	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	2.2E-18	175	233	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.269	175	233	IPR001471	AP2/ERF domain
SMART	SM00380	3.3E-30	175	239	IPR001471	AP2/ERF domain
Pfam	PF00847	3.7E-10	176	225	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.0E-6	215	235	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 333 aa Download sequence Send to blast
VAPRKEQGGV KEGCTKEGAL SLAVNNTDGE RVKSSRKVTV SKKEAKAVET TSTDDSTKKK 60 KKVVESFGQR TSIYRGVTRH RWTGRYEAHL WDNSCRREGQ ARKGRQVYLG GYDKEDKAAR 120 AYDLAALKYW GPAATTNFQI ASYSKELEEM NHMTKQEFIA SIRRKSSGFS RGASMYRGVT 180 RHHQQGRWQA RIGRVAGNKD LYLGTFATEE EAAEAYDIAA IKFRGINAVT NFEMNRYDVE 240 AIMNSSFPVG GSAVKRHKQL SLESPPPPTD DHNIQQLLLP SSSVELDPNS IPCGIPFDPS 300 VLYHPQNFFQ HYPDPTVPMN QADQFFMWSN QSY

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Confined to the central region of inflorescence ane floral meristems, progressively restricted to the innermost cells of the dome. Also detected in developing stamen locules and later in sporogonous cells within locules. In carpel primordia, found in placenta and in young ovule primordia. {ECO:0000269\|PubMed:15988559}.
Uniprot	TISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves. {ECO:0000269\|PubMed:15988559}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009150822.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK353404	0.0	AK353404.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-30-G24.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009150822.2	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor AIL7 isoform X2
Refseq	XP_018514933.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor AIL7 isoform X1
Swissprot	Q6J9N8	1e-165	AIL7_ARATH; AP2-like ethylene-responsive transcription factor AIL7
TrEMBL	A0A397Z0E9	0.0	A0A397Z0E9_BRACM; Uncharacterized protein
TrEMBL	M4E6J0	0.0	M4E6J0_BRARP; Uncharacterized protein
STRING	Bra024394.1-P	0.0	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3333	27	65

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65510.1	1e-158	AINTEGUMENTA-like 7

Publications ? help Back to Top
Todd J,Post-Beittenmiller D,Jaworski JG KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana. Plant J., 1999. 17(2): p. 119-30 [PMID:10074711] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398]