PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

C2H2

Protein Properties

Length: 213aa MW: 23038.1 Da PI: 7.634

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009136525.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.9	3.7e-05	89	111	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ykC+ CgksF++ L H +H XP_009136525.1 89 YKCSVCGKSFPSYQALGGHKTSH 111 9***********99998888777 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.11E-9	88	111	No hit	No description
PROSITE profile	PS50157	10.783	89	116	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0022	89	111	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	2.5E-4	89	111	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF13912	1.3E-14	89	113	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	91	111	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	1.11E-9	144	171	No hit	No description
Pfam	PF13912	4.3E-12	148	173	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	9.12	149	171	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.35	149	171	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	151	171	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 213 aa Download sequence Send to blast
MALDTLNSPT STTAPPPFLT EPENLESWTK RKRTKRHRTV DQSHPPSEEE YLAICLLMLA 60 RGSSSSSSND GNDHHSPPAP PSDHHHRDYK CSVCGKSFPS YQALGGHKTS HRKPVSNTNC 120 QDTNNSGNGS VTNKGNISNG LIGQSGKTHK CSICFKSFPS GQALGGHKRC HYDGGNGNGS 180 NNHGFDLNLP ADHDETLVKS QLSGEELKSE SDY

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Highly expressed in roots and at lower levels in leaves and stems. {ECO:0000269\|PubMed:10806347, ECO:0000269\|PubMed:15333755}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions. Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner. {ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:21852415}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00399	DAP	Transfer from AT3G49930	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009136525.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By abscisic acid (ABA), ethylene, dehydration, salt and cold. {ECO:0000269\|PubMed:10806347, ECO:0000269\|PubMed:15333755, ECO:0000269\|PubMed:21852415}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009136525.1	1e-157	PREDICTED: zinc finger protein AZF1 isoform X1
Swissprot	Q9SSW1	2e-61	AZF1_ARATH; Zinc finger protein AZF1
TrEMBL	M4D8V4	1e-155	M4D8V4_BRARP; Uncharacterized protein
STRING	Bra012914.1-P	1e-156	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3121	22	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G49930.1	4e-71	C2H2 family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]