PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

MYB

Protein Properties

Length: 304aa MW: 35352 Da PI: 4.6476

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009134903.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	56.3	7.5e-18	21	68	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT+eEd +l ++++ +G g+W++ +r+ g+ Rt+k+c++rw++yl XP_009134903.1 21 RGPWTAEEDFKLTNYIATHGEGRWNSLSRCAGLQRTGKSCRLRWLNYL 68 89********************************************97 PP
2	Myb_DNA-binding	50.6	4.4e-16	74	117	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 rg+ T eE++l+++++ ++G++ W++Ia++++ gRt++++k++w++ XP_009134903.1 74 RGNITLEEQLLILELHSRWGNR-WSKIAQYLP-GRTDNEIKNYWRT 117 7999****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	14.351	16	68	IPR017930	Myb domain
SuperFamily	SSF46689	3.48E-31	18	115	IPR009057	Homeodomain-like
SMART	SM00717	2.3E-14	20	70	IPR001005	SANT/Myb domain
Pfam	PF00249	1.5E-15	21	68	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	8.0E-23	22	75	IPR009057	Homeodomain-like
CDD	cd00167	7.93E-11	23	68	No hit	No description
PROSITE profile	PS51294	22.917	69	123	IPR017930	Myb domain
SMART	SM00717	2.9E-14	73	121	IPR001005	SANT/Myb domain
Pfam	PF00249	7.3E-15	74	117	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	2.3E-22	76	122	IPR009057	Homeodomain-like
CDD	cd00167	1.43E-6	94	117	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 304 aa Download sequence Send to blast
MDEKGRSFKN NNMEDEMDLK RGPWTAEEDF KLTNYIATHG EGRWNSLSRC AGLQRTGKSC 60 RLRWLNYLRP DVRRGNITLE EQLLILELHS RWGNRWSKIA QYLPGRTDNE IKNYWRTRVQ 120 KHAKQLKCDV NSQQFKDTMK YMWMPRLVER IQSAAASLTS TTGSATTSSC ITTSNNEFMT 180 YDYNNNNFIG ERLGVMNNND YITPENSSVA VSPVSDLTDY YNAPKPNPDQ NLVGPQMLPD 240 NYFDYSGLLD EDLTATHEQS NLDWFENIDE VVSSSSESLW NIGESDEDFW FCQQQQQFNN 300 NNDF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	8e-25	18	115	24	120	MYB TRANSFORMING PROTEIN
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed specifically in flowers. Restricted to anthers in maturing flowers. Strongest expression in the vascular and connective tissue where the anther attaches to the filament. Not detected in pollen. {ECO:0000269\|PubMed:19091873}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor contributing to the regulation of stamen maturation and male fertility in response to jasmonate signaling. Required for correct timing of anther dehiscence. Acts as a negative regulator of abscisic acid-induced cell death. Not involved in the regulation of BOI. Regulated by MYB21 and at a lower level by MYB24. Negatively regulated by the proteasome in an SCF(COI1) E3 ubiquitin-protein ligase complex-dependent manner. {ECO:0000269\|PubMed:14555693, ECO:0000269\|PubMed:19091873, ECO:0000269\|PubMed:20921156, ECO:0000269\|PubMed:23952703}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009134903.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by jasmonate and pathogen infection. {ECO:0000269\|PubMed:14555693, ECO:0000269\|PubMed:19091873}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF738287	0.0	KF738287.1 Brassica napus MYB transcription factor 108-2 (MYB108-2.1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009134903.1	0.0	PREDICTED: transcription factor MYB108-like isoform X1
Swissprot	Q9LDE1	1e-162	MY108_ARATH; Transcription factor MYB108
TrEMBL	A0A3P5ZN60	0.0	A0A3P5ZN60_BRACM; Uncharacterized protein
TrEMBL	M4CAH3	0.0	M4CAH3_BRARP; Uncharacterized protein
STRING	Bra001202.1-P	0.0	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4	28	2646

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G06490.1	1e-154	myb domain protein 108

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Cheng HQ, et al. The cotton MYB108 forms a positive feedback regulation loop with CML11 and participates in the defense response against Verticillium dahliae infection. J. Exp. Bot., 2016. 67(6): p. 1935-50 [PMID:26873979] Sanz-Fernández M, et al. Screening Arabidopsis mutants in genes useful for phytoremediation. J. Hazard. Mater., 2017. 335: p. 143-151 [PMID:28441590] Chou ML, et al. The Direct Involvement of Dark-Induced Tic55 Protein in Chlorophyll Catabolism and Its Indirect Role in the MYB108-NAC Signaling Pathway during Leaf Senescence in Arabidopsis thaliana. Int J Mol Sci, 2018. [PMID:29937503]