PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

MIKC_MADS

Protein Properties

Length: 209aa MW: 23895.7 Da PI: 9.7822

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009132582.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	89.6	1.6e-28	9	59	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 k+ien++ rqvtfskRr g++KKA+ELSvLCda+va iifs++g+ly+++s XP_009132582.1 9 KKIENTTSRQVTFSKRRSGLFKKAHELSVLCDAQVAAIIFSQKGRLYDFAS 59 68***********************************************86 PP
2	K-box	60.1	9.1e-21	84	171	10	97
K-box 10 eeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkk 97 +e+ + l++e+ + ++ie+L+ + +l+G++L +slkeLq++ +q+eksl +Rs+K +l+ +++e+l+ k +el++e +L+ + XP_009132582.1 84 TEQYVQGLKKEMVTMVEKIEMLEVHNQKLMGKSLAFCSLKELQEIATQIEKSLHIVRSRKAKLYEDEVEKLKAKGRELKDERVRLSGR 171 6788899**************999*****************************************************9998765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	2.1E-40	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	31.511	1	61	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	2.7E-29	3	23	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	2.22E-31	3	88	IPR002100	Transcription factor, MADS-box
CDD	cd00265	7.30E-41	3	74	No hit	No description
Pfam	PF00319	4.5E-26	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	2.7E-29	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	2.7E-29	38	59	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	5.7E-19	88	170	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	11.487	88	178	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 209 aa Download sequence Send to blast
MVRGKIQIKK IENTTSRQVT FSKRRSGLFK KAHELSVLCD AQVAAIIFSQ KGRLYDFASS 60 DIQKTIKRYA EYKGEYFVAE SHPTEQYVQG LKKEMVTMVE KIEMLEVHNQ KLMGKSLAFC 120 SLKELQEIAT QIEKSLHIVR SRKAKLYEDE VEKLKAKGRE LKDERVRLSG RVGEEPSGMP 180 MPSGSKEKED VETDLSIGFR PDLNILLVP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5f28_A	4e-21	1	93	1	90	MEF2C
5f28_B	4e-21	1	93	1	90	MEF2C
5f28_C	4e-21	1	93	1	90	MEF2C
5f28_D	4e-21	1	93	1	90	MEF2C
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Bra.24142	1e-175	flower\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in the shoot apical meristem (SAM) during the vegetative phase and the floral transition. After floral transition, expressed in apical meristem (AM), inflorescence meristem (IM) and floral primordia. {ECO:0000269\|PubMed:21609362}.

Functional Description ? help Back to Top
Source	Description
UniProt	MADS-box transcription factor that acts with AGL42 and AGL71 in the control of flowering time. Promotes flowering at the shoot apical and axillary meristems. Seems to act through a gibberellin-dependent pathway. Interacts genetically with SOC1 and its expression is directly regulated by SOC1. {ECO:0000269\|PubMed:21609362}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009132582.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009132583.1	1e-152	PREDICTED: MADS-box protein AGL72-like
Refseq	XP_009132584.1	1e-152	PREDICTED: MADS-box protein AGL72-like
Refseq	XP_013640563.1	1e-152	MADS-box protein AGL72-like
Refseq	XP_022571027.1	1e-152	MADS-box protein AGL72-like
Swissprot	Q9FLH5	1e-115	AGL72_ARATH; MADS-box protein AGL72
TrEMBL	A0A398A2H2	1e-150	A0A398A2H2_BRACM; Uncharacterized protein
TrEMBL	M4EK38	1e-150	M4EK38_BRARP; Uncharacterized protein
STRING	Bra029155.1-P	1e-151	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM78	28	413

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G51860.2	1e-120	MIKC_MADS family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]