PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

ERF

Protein Properties

Length: 212aa MW: 23480.8 Da PI: 4.6934

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009125951.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.1	1.2e-19	15	65	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +++ GVr+++ +gr++AeIrdp++ + r++lg+f+taeeAa a+++a+++++g XP_009125951.1 15 TKFLGVRRRP-WGRYAAEIRDPTT---KERHWLGTFDTAEEAALAYDRAARSMRG 65 5899****.******965...5***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	6.05E-32	15	72	No hit	No description
Gene3D	G3DSA:3.30.730.10	2.9E-29	16	73	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	20.719	16	73	IPR001471	AP2/ERF domain
Pfam	PF00847	2.8E-12	16	65	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.16E-21	16	74	IPR016177	DNA-binding domain
SMART	SM00380	2.3E-34	16	79	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.3E-8	17	28	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.3E-8	39	55	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 212 aa Download sequence Send to blast
MNTSKSKKKQ EEAGTKFLGV RRRPWGRYAA EIRDPTTKER HWLGTFDTAE EAALAYDRAA 60 RSMRGTRART NFVYSDMPPS SSVTSIISPD DPTPTPPPPP PAATPCSDDP VDYLMMFNQY 120 SSTDSPMLQP AQVESSYMFG GSPSCYSNSS SDLPPLPSDL SNSCYSQQPW SVEDYSSANY 180 FEGEYVHSPM FSTMPSVSDS LPQGFNHFGS YN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	2e-20	14	72	3	62	ATERF1
3gcc_A	2e-20	14	72	3	62	ATERF1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in germinating seeds. Present in young shoots, at low levels, especially in leaf primordia and developing leaf blades. Also detected in vascular tissue, mostly in xylem, of young leaves, petioles and hypocotyls. {ECO:0000269\|PubMed:11044410, ECO:0000269\|PubMed:12472696, ECO:0000269\|PubMed:16339853}.

Functional Description ? help Back to Top
Source	Description
UniProt	Cell division-promoting factor involved in leaf blade differentiation, inflorescence branching, as well as in carpel and silique shape. Promotes the number of xylem cells. Regulates positively the gibberellin signaling pathway leading to germination, hypocotyl elongation, and leaf expansion. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269\|PubMed:11044410, ECO:0000269\|PubMed:12472696, ECO:0000269\|PubMed:16339853}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009125951.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By imbibition. {ECO:0000269\|PubMed:16339853}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009125951.1	1e-155	PREDICTED: ethylene-responsive transcription factor LEP-like
Swissprot	Q9M644	2e-96	LEP_ARATH; Ethylene-responsive transcription factor LEP
TrEMBL	A0A398A6A7	1e-154	A0A398A6A7_BRACM; Uncharacterized protein
STRING	Bra023440.1-P	1e-148	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G13910.1	4e-63	ERF family protein

Publications ? help Back to Top
van der Graaff E,Nussbaumer C,Keller B The Arabidopsis thaliana rlp mutations revert the ectopic leaf blade formation conferred by activation tagging of the LEP gene. Mol. Genet. Genomics, 2003. 270(3): p. 243-52 [PMID:12910411] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Chandler JW Class VIIIb APETALA2 Ethylene Response Factors in Plant Development. Trends Plant Sci., 2018. 23(2): p. 151-162 [PMID:29074232]