PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

bHLH

Protein Properties

Length: 94aa MW: 10604.8 Da PI: 9.3621

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009121603.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	23.5	1e-07	19	60	14	54
HHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 14 driNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 d+i + +++Lr+ +P+ + + +s +s + +L+++++YI++L XP_009121603.1 19 DQITDLISKLRQSIPEiRQNRRSSTVSASKVLQETCNYIRNL 60 799***********998888888999**********98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	10.474	5	60	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	6.0E-5	19	60	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.97E-8	19	85	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.6E-8	19	63	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 94 aa Download sequence Send to blast
MSSSRRSRQA SSSSRISDDQ ITDLISKLRQ SIPEIRQNRR SSTVSASKVL QETCNYIRNL 60 NKEADDLSDR LSQLLETIDP NSPQAAIIRS LINE

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, leaves, stems and flowers. {ECO:0000269\|PubMed:16527868}.

Functional Description ? help Back to Top
Source	Description
UniProt	Atypical and probable non DNA-binding bHLH transcription factor that integrates multiple signaling pathways to regulate cell elongation and plant development. Regulates light responses by binding and inhibiting the activity of the bHLH transcription factor HFR1, a critical regulator of light signaling and shade avoidance. May have a regulatory role in various aspects of gibberellin-dependent growth and development. {ECO:0000269\|PubMed:16527868, ECO:0000269\|PubMed:20305124}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009121603.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by exogenous gibberellin. {ECO:0000269\|PubMed:16527868}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC189232	6e-63	AC189232.1 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrB013N08, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009121603.1	4e-58	PREDICTED: transcription factor PRE2
Swissprot	Q9LXG5	5e-46	PRE2_ARATH; Transcription factor PRE2
TrEMBL	A0A397XNI8	8e-57	A0A397XNI8_BRACM; Uncharacterized protein
TrEMBL	M4CWW9	8e-57	M4CWW9_BRARP; Uncharacterized protein
STRING	Bra008716.1-P	1e-57	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM259	28	225

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15160.1	7e-48	BANQUO 2

Publications ? help Back to Top
Jung S, et al. Synteny conservation between the Prunus genome and both the present and ancestral Arabidopsis genomes. BMC Genomics, 2006. 7: p. 81 [PMID:16615871] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Mao WT, et al. The C-Terminal Sequence and PI motif of the Orchid (Oncidium Gower Ramsey) PISTILLATA (PI) Ortholog Determine its Ability to Bind AP3 Orthologs and Enter the Nucleus to Regulate Downstream Genes Controlling Petal and Stamen Formation. Plant Cell Physiol., 2015. 56(11): p. 2079-99 [PMID:26423960] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]