PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

bHLH

Protein Properties

Length: 213aa MW: 23935.4 Da PI: 9.9319

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009115703.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.5	1.1e-08	138	178	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L XP_009115703.1 138 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 178 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	129	178	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	3.9E-14	130	188	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.03E-14	133	189	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.3E-14	135	184	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.6E-6	139	178	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.39E-6	152	183	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 213 aa Download sequence Send to blast
MDNSDILMNM MMTQMEKLPD HFSNPNLNPS SHNITMPSES NTYHPFFFNH NNHTHPPVLN 60 PTITHHHQPG LNFRYAPSTS SFLPDKRGGG GDNADMAAMR EMIFRIAVMQ PIHIDPESVK 120 PPKRKNVRIS KDPQSVAARH RRERISERIR ILQRLVPGGT KMDTASMLDE AIHYVKFLKK 180 QVQSLEEHAV VNGGGMTPAP PVVGGKGCKD YAI

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed in the developing septum, transmitting tract and stigma. {ECO:0000269\|PubMed:17855426}.
Uniprot	TISSUE SPECIFICITY: Gynoecium. {ECO:0000269\|PubMed:17855426}.

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009115703.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009115703.1	1e-158	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	3e-97	HEC2_ARATH; Transcription factor HEC2
TrEMBL	M4F4R7	1e-157	M4F4R7_BRARP; Uncharacterized protein
STRING	Bra036071.1-P	1e-158	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	4e-87	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]