PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica

Family

C2H2

Protein Properties

Length: 418aa MW: 47265.8 Da PI: 7.2878

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009104072.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.9	3.8e-05	208	227	1	20
EEETTTTEEESSHHHHHHHH CS zf-C2H2 1 ykCpdCgksFsrksnLkrHi 20 ++Cp C k+F+r n++ H+ XP_009104072.1 208 FSCPVCFKTFNRYNNMQMHM 227 89*****************9 PP
2	zf-C2H2	14.2	0.00013	292	314	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C +Cgk F + + ++H +++ XP_009104072.1 292 FMCRKCGKAFAVRGDWRTHEKNC 314 89*****************9987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	10.076	208	235	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	6.2E-6	208	227	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.38	208	230	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	210	230	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	2.09E-6	274	312	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.2E-5	288	312	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	49	292	312	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	8.808	292	312	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009860	Biological Process	pollen tube growth
GO:0010500	Biological Process	transmitting tissue development
GO:1990058	Biological Process	fruit replum development
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 418 aa Download sequence Send to blast
MTDPHSNFFT DWFKSNPVHH YPNFSTNPPA LPPPSSFFFF PHSGDLCRPP PPPTPPSSPP 60 LREALPLLSL SPANKQQDHH GHLIQEPTST SIDVDDYYHH HHQDDQNNDD HDITVALHIG 120 LPSPSTQEMA SFLTLSSSSS SSRTTHHHEN MNNQKDLDND YHHEGTGGGE DDDEDSVGGD 180 GACRISRLNK GQYWIPTPSQ ILIGPTQFSC PVCFKTFNRY NNMQMHMWGH GSEYRKGPES 240 LRGTQPTGML RLPCYCCAPG CRNNIDHPRA KPLKDFRTLQ THYKRKHGIK PFMCRKCGKA 300 FAVRGDWRTH EKNCGKLWYC ICGSDFKHKR SLKDHIKAFG NGHGAYGIDG FDDEDETASE 360 DLYNLKSCGK QSTGTSSCLF SPVFLAMYNN EVPLLHGIYL LTYIILSFIY VSFRRNRS

Sequence ? help Back to Top

Protein Sequence Length: 418 aa Download sequence Send to blast

MTDPHSNFFT DWFKSNPVHH YPNFSTNPPA LPPPSSFFFF PHSGDLCRPP PPPTPPSSPP  60
LREALPLLSL SPANKQQDHH GHLIQEPTST SIDVDDYYHH HHQDDQNNDD HDITVALHIG  120
LPSPSTQEMA SFLTLSSSSS SSRTTHHHEN MNNQKDLDND YHHEGTGGGE DDDEDSVGGD  180
GACRISRLNK GQYWIPTPSQ ILIGPTQFSC PVCFKTFNRY NNMQMHMWGH GSEYRKGPES  240
LRGTQPTGML RLPCYCCAPG CRNNIDHPRA KPLKDFRTLQ THYKRKHGIK PFMCRKCGKA  300
FAVRGDWRTH EKNCGKLWYC ICGSDFKHKR SLKDHIKAFG NGHGAYGIDG FDDEDETASE  360
DLYNLKSCGK QSTGTSSCLF SPVFLAMYNN EVPLLHGIYL LTYIILSFIY VSFRRNRS

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in developing carpels (PubMed:17600712). Expressed in the shoot apical meristem and the replum (PubMed:25039392). {ECO:0000269\|PubMed:17600712}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional regulator required for normal differentiation of the ovary transmitting tract cells and pollen tube growth. In Arabidopsis, the transmitting tract facilitates the transport of pollen tubes to the ovules for fertilization (PubMed:17600712). May play a role in the regulation of AGL8/FUL, which is required for normal pattern of cell division, expansion and differentiation during morphogenesis of the silique (PubMed:23515580). Plays a role in replum development by the activation of the homeobox protein KNAT1 (PubMed:25039392). {ECO:0000269\|PubMed:17600712, ECO:0000269\|PubMed:23515580, ECO:0000269\|PubMed:25039392}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_009104072.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF254447	0.0	AF254447.1 Arabidopsis thaliana WIP2 protein (WIP2) mRNA, complete cds.
GenBank	BT021089	0.0	BT021089.1 Arabidopsis thaliana At3g57670 gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009104072.1	0.0	PREDICTED: zinc finger protein WIP2 isoform X1
Swissprot	Q9SVY1	0.0	ZWIP2_ARATH; Zinc finger protein WIP2
TrEMBL	A0A3P6BK25	0.0	A0A3P6BK25_BRACM; Uncharacterized protein
STRING	Bo6g073120.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM239	28	237

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G57670.1	1e-176	C2H2 family protein

Publications ? help Back to Top
Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656]