PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer

Family

WOX

Protein Properties

Length: 302aa MW: 33888.1 Da PI: 6.6025

Description

WOX family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_004512229.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	62	8.8e-20	28	89	2	57
T--SS--HHHHHHHHHHHHH..SSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 2 rkRttftkeqleeLeelFek..nrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 ++R+t+t++q+++L++l+++ r psae++++++++l +++ ++V++WFqN++a+e++ XP_004512229.1 28 STRWTPTTDQIRILKDLYYNngIRSPSAEQIQRISARLrqygKIEGKNVFYWFQNHKARERQ 89 58***************8567***********************************97 PP
2	Wus_type_Homeobox	113.5	1.1e-36	27	91	2	65
Wus_type_Homeobox 2 artRWtPtpeQikiLeelyk.sGlrtPnkeeiqritaeLeeyGkiedkNVfyWFQNrkaRerqkq 65 ++tRWtPt++Qi+iL++ly+ +G+r+P++e+iqri+a+L++yGkie+kNVfyWFQN+kaRerqk+ XP_004512229.1 27 SSTRWTPTTDQIRILKDLYYnNGIRSPSAEQIQRISARLRQYGKIEGKNVFYWFQNHKARERQKK 91 789*************9779***************************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	4.0E-8	5	89	IPR009057	Homeodomain-like
SuperFamily	SSF46689	9.84E-12	21	95	IPR009057	Homeodomain-like
PROSITE profile	PS50071	10.916	24	90	IPR001356	Homeobox domain
SMART	SM00389	1.3E-5	26	94	IPR001356	Homeobox domain
Pfam	PF00046	3.5E-17	29	89	IPR001356	Homeobox domain
CDD	cd00086	8.30E-7	29	91	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010492	Biological Process	maintenance of shoot apical meristem identity
GO:0080166	Biological Process	stomium development
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 302 aa Download sequence Send to blast
MEQQQQQTGN EEGGGSSGKG GYMSRQSSTR WTPTTDQIRI LKDLYYNNGI RSPSAEQIQR 60 ISARLRQYGK IEGKNVFYWF QNHKARERQK KRFTSDHNNN NNNNNLPMQR SATITNNVAV 120 AAWKQIEEQQ SPIIQHKYSN NIISSTGLSS ASCSSAEMVT VGQIGNYGYG SVPMEKSFRE 180 CTISAGCSSG HVGSTINHHL GWVGHVGPYS STYANLFEKI RPEEEIMEEE QEEENGSPEI 240 ETLPLFPMHG EDIHGYCNLK SNSSNYGAPS WYQAEDGFIN ASRTTSLELS LNSYTRRSPD 300 YA

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that plays a central role during developmental processes such as early embryogenesis and flowering, probably by regulating expression of specific genes. Required to specify stem cell identity in meristems, such as shoot apical meristem (SAM). Acts in parallel with HAM. {ECO:0000269\|PubMed:12208843}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00265	DAP	Transfer from AT2G17950	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_004512229.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	FJ477681	1e-128	FJ477681.1 Medicago truncatula WUSCHEL (WUS) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004512229.1	0.0	protein WUSCHEL
Swissprot	Q8LL11	7e-82	WUS_PETHY; Protein WUSCHEL
TrEMBL	A0A1S2YZ61	0.0	A0A1S2YZ61_CICAR; protein WUSCHEL
STRING	XP_004512229.1	0.0	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF8241	33	45

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G17950.1	6e-40	WOX family protein

Publications ? help Back to Top
Stuurman J,Jäggi F,Kuhlemeier C Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells. Genes Dev., 2002. 16(17): p. 2213-8 [PMID:12208843]