PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Cicereae; Cicer

Family

ERF

Protein Properties

Length: 216aa MW: 24800.1 Da PI: 5.825

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_004501409.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	54.5	2.9e-17	27	75	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ykGVr +k +g+Wv+eIr p++ r r++lg++++ae+Aa+a +aa +l+g XP_004501409.1 27 YKGVRKRK-WGKWVSEIRLPNS---RERIWLGSHDSAEKAARAFDAALYCLRG 75 9**999.******933...5***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	3.8E-28	26	89	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.81E-20	26	84	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	3.4E-28	26	84	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.351	26	83	IPR001471	AP2/ERF domain
Pfam	PF00847	5.0E-10	27	75	IPR001471	AP2/ERF domain
CDD	cd00018	1.56E-27	27	85	No hit	No description
PRINTS	PR00367	9.5E-9	27	38	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.5E-9	49	65	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 216 aa Download sequence Send to blast
MNVDMDHVSD STTHDKKKCE ENKKKMYKGV RKRKWGKWVS EIRLPNSRER IWLGSHDSAE 60 KAARAFDAAL YCLRGRHANF NFPDTPFNLV NNVNNYNNSL TPQQIQQIAS NFANNINQPP 120 TNVVDNNNHN NAASSSSNTS TIDWTFLNAL DASTEDANFI HNYGDLEKMH SGELLYSIPP 180 PFFEDDNNRN QIEANIDAGD YDDPFSHPSF LWNWNF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	3e-15	27	93	15	81	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	15	33	KKKCEENKKKMYKGVRKRK
2	27	33	KGVRKRK

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_004501409.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004501409.1	1e-160	ethylene-responsive transcription factor ERF017-like
Swissprot	Q9S7L5	4e-39	ERF18_ARATH; Ethylene-responsive transcription factor ERF018
TrEMBL	A0A1S2Y9B6	1e-159	A0A1S2Y9B6_CICAR; ethylene-responsive transcription factor ERF017-like
STRING	XP_004501409.1	1e-160	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1479	33	99

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G21960.1	5e-32	ERF family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Chen HY, et al. ORA47 (octadecanoid-responsive AP2/ERF-domain transcription factor 47) regulates jasmonic acid and abscisic acid biosynthesis and signaling through binding to a novel cis-element. New Phytol., 2016. 211(2): p. 599-613 [PMID:26974851] Hickman R, et al. Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network. Plant Cell, 2017. 29(9): p. 2086-2105 [PMID:28827376]