PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans

Family

TCP

Protein Properties

Length: 462aa MW: 51036.4 Da PI: 7.0727

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
WALNUT_00024380-RA	genome	JHU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	67.8	3.6e-21	35	96	4	65
TCP 4 kkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt 65 +++ + ++hTkv+gR RRvR++++c +F L++eLG+ +d++ti+WLl q p +++ WALNUT_00024380-RA 35 RRRLTGDRHTKVEGRHRRVRIPITCCPGIFRLTEELGHRSDGQTIQWLLSQVRPDLVLSPNS 96 677899**********************************************9988776666 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51369	16.982	39	93	IPR017887	Transcription factor TCP subgroup
Pfam	PF03634	3.2E-16	40	89	IPR005333	Transcription factor, TCP
Gene3D	G3DSA:3.60.110.10	3.0E-68	141	424	IPR003010	Carbon-nitrogen hydrolase
SuperFamily	SSF56317	8.37E-66	141	431	IPR003010	Carbon-nitrogen hydrolase
PROSITE profile	PS50263	40.218	142	449	IPR003010	Carbon-nitrogen hydrolase
CDD	cd07564	9.68E-121	142	429	No hit	No description
Pfam	PF00795	7.1E-58	143	421	IPR003010	Carbon-nitrogen hydrolase
PROSITE pattern	PS00920	0	174	189	IPR000132	Nitrilase/cyanide hydratase, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0019499	Biological Process	cyanide metabolic process
GO:0051410	Biological Process	detoxification of nitrogen compound
GO:0018822	Molecular Function	nitrile hydratase activity
GO:0047427	Molecular Function	cyanoalanine nitrilase activity
GO:0047558	Molecular Function	3-cyanoalanine hydratase activity
GO:0080061	Molecular Function	indole-3-acetonitrile nitrilase activity

Sequence ? help Back to Top
Protein Sequence Length: 462 aa Download sequence Send to blast
MEVQPQSSAE NVVGELPLKI IQQQQLSPEE QLLKRRRLTG DRHTKVEGRH RRVRIPITCC 60 PGIFRLTEEL GHRSDGQTIQ WLLSQVRPDL VLSPNSSLSR PGHHSASADS VPGRFDLPIC 120 TSRIDEDDLD QKAVALLQRL TVRATVVQAS TVFYNTIATL DKAERLIAGA AAYGSQLVVF 180 PEAFVGGYPH GMMFEASTET HLTLENKEFQ KYFASAIDVP GPEVDRLAKI SGKYKVHLVM 240 GVVERVGYSL FSAILFFDSL GRYLGKHRKL MPMASERAVW RPGEKSLLPV YETSIGKIGG 300 LICWDNRMPS LRTELYDKGI EIYCAPTAEA REIWRASMTH IALEGGCFVL SANQFCRRKD 360 YFLSTECVSE GSNGDISQDK IVCAGGSVII SPSGTILAGP NYQGESLISA DLDLGEIVQA 420 KLDFGGIGHL VGPNSVKWTP DKNNSNLLRT PVKTEVPDLQ QW

Sequence ? help Back to Top

Protein Sequence Length: 462 aa Download sequence Send to blast

MEVQPQSSAE NVVGELPLKI IQQQQLSPEE QLLKRRRLTG DRHTKVEGRH RRVRIPITCC  60
PGIFRLTEEL GHRSDGQTIQ WLLSQVRPDL VLSPNSSLSR PGHHSASADS VPGRFDLPIC  120
TSRIDEDDLD QKAVALLQRL TVRATVVQAS TVFYNTIATL DKAERLIAGA AAYGSQLVVF  180
PEAFVGGYPH GMMFEASTET HLTLENKEFQ KYFASAIDVP GPEVDRLAKI SGKYKVHLVM  240
GVVERVGYSL FSAILFFDSL GRYLGKHRKL MPMASERAVW RPGEKSLLPV YETSIGKIGG  300
LICWDNRMPS LRTELYDKGI EIYCAPTAEA REIWRASMTH IALEGGCFVL SANQFCRRKD  360
YFLSTECVSE GSNGDISQDK IVCAGGSVII SPSGTILAGP NYQGESLISA DLDLGEIVQA  420
KLDFGGIGHL VGPNSVKWTP DKNNSNLLRT PVKTEVPDLQ QW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3wuy_A	6e-38	141	439	15	307	Nitrilase
3wuy_B	6e-38	141	439	15	307	Nitrilase
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	33	37	KRRRL

Functional Description ? help Back to Top
Source	Description
UniProt	Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN). Not associated with auxin production but may be involved in cyanide detoxification. {ECO:0000269\|PubMed:10574458, ECO:0000269\|PubMed:11060302}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not induced by abscisic acid or by 1-aminocyclopropane-1-carboxylic acid (ACC). {ECO:0000269\|PubMed:10574458}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018820046.1	0.0	PREDICTED: bifunctional nitrilase/nitrile hydratase NIT4B-like
Swissprot	Q42966	1e-146	NRL4B_TOBAC; Bifunctional nitrilase/nitrile hydratase NIT4B
TrEMBL	A0A2I4EKX2	0.0	A0A2I4EKX2_JUGRE; bifunctional nitrilase/nitrile hydratase NIT4B-like
STRING	XP_008243489.1	0.0	(Prunus mume)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4583	8	8

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G45680.1	3e-19	TCP family protein

Publications ? help Back to Top
Dohmoto M,Sano J,Tsunoda H,Yamaguchi K Structural analysis of the TNIT4 genes encoding nitrilase-like protein from tobacco. DNA Res., 1999. 6(5): p. 313-7 [PMID:10574458] Piotrowski M,Schönfelder S,Weiler EW The Arabidopsis thaliana isogene NIT4 and its orthologs in tobacco encode beta-cyano-L-alanine hydratase/nitrilase. J. Biol. Chem., 2001. 276(4): p. 2616-21 [PMID:11060302]