PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID WALNUT_00016560-RA
Organism
Juglans regia
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans
Family HD-ZIP
Protein Properties Length: 762aa    MW: 84585.5 Da    PI: 7.1769
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
WALNUT_00016560-RAgenomeJHUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox642.1e-202277156
                        TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
            Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                        +++ +++t++q++ Le++F+++++p++++r +L+++lgL  rq+k+WFqNrR+++k
  WALNUT_00016560-RA 22 KKRYHRHTAHQIQKLEAMFKECPHPDEKQRLQLSRELGLAPRQIKFWFQNRRTQMK 77
                        678899***********************************************998 PP
2START138.57.1e-442194012165
                         HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....E CS
               START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....k 78 
                         +a +a++el+++++ +ep+W+ks+    + ++ + + ++f+++++       ++ea+r+sgvv+m+   lv  ++d++ +W e ++     
  WALNUT_00016560-RA 219 IAARAMEELLRLVQTNEPLWMKSAtdgrDALDFESYERIFPRANSnlknphLRIEASRDSGVVIMNGLSLVDMFMDSN-KWVELFPtivlV 308
                         6889***********************999************999*********************************.*******9999* PP

                         EEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEE CS
               START  79 aetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghs 162
                         a+tlevissg      g lqlm+ elq+ls lvp R+f+f+Ry++q ++g w+ivdvS d ++ ++  +s  R+++lpSg+li++++ng+s
  WALNUT_00016560-RA 309 AKTLEVISSGmlgshsGSLQLMYEELQVLSSLVPtREFYFLRYCQQIEQGLWAIVDVSYDFPRGNQ-FASESRCHRLPSGCLIQDMPNGYS 398
                         *****************************************************************9.7999******************** PP

                         EEE CS
               START 163 kvt 165
                         kv+
  WALNUT_00016560-RA 399 KVF 401
                         *96 PP
3START29.41.8e-10448492163206
                         EEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
               START 163 kvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                         +vtwvehv+ +++ p h l+r l++sgla+ga +w+a l r ce+
  WALNUT_00016560-RA 448 QVTWVEHVEIEDKNPtHRLYRDLIHSGLAFGAERWLAILCRMCER 492
                         69***************************************9996 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466893.18E-201079IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.607.4E-221781IPR009057Homeodomain-like
PROSITE profilePS5007118.0421979IPR001356Homeobox domain
SMARTSM003891.1E-192083IPR001356Homeobox domain
CDDcd000867.29E-192180No hitNo description
PfamPF000465.7E-182277IPR001356Homeobox domain
PROSITE patternPS0002705477IPR017970Homeobox, conserved site
PROSITE profilePS5084846.313209495IPR002913START domain
SuperFamilySSF559611.29E-30210396No hitNo description
CDDcd088756.71E-109213491No hitNo description
SMARTSM002347.8E-39218492IPR002913START domain
PfamPF018522.0E-36219401IPR002913START domain
Gene3DG3DSA:3.30.530.201.1E-4306418IPR023393START-like domain
SuperFamilySSF559611.29E-30446493No hitNo description
PfamPF018521.9E-6448492IPR002913START domain
SuperFamilySSF559612.47E-24514754No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 762 aa     Download sequence    Send to blast
MEYGGGDGGD HHDAFFDPQR RKKRYHRHTA HQIQKLEAMF KECPHPDEKQ RLQLSRELGL  60
APRQIKFWFQ NRRTQMKAQH ERADNCSLRA ENDKIRCENI AIREALRNVI CPSCGGPPVN  120
EDSYFDEQKL RMENSQLKEE LDRISSIAAK YIGRPISQLP PVQPINISSL DLSMGSFGGQ  180
GIGGPSLDLD LLPGSSSVVP SLPFQPCLSD MDKSLMTDIA ARAMEELLRL VQTNEPLWMK  240
SATDGRDALD FESYERIFPR ANSNLKNPHL RIEASRDSGV VIMNGLSLVD MFMDSNKWVE  300
LFPTIVLVAK TLEVISSGML GSHSGSLQLM YEELQVLSSL VPTREFYFLR YCQQIEQGLW  360
AIVDVSYDFP RGNQFASESR CHRLPSGCLI QDMPNGYSKV FFKFIIKCVS HWLYISIPTT  420
IKHSTNFHSP TISIGIVFTQ SSWKMPKQVT WVEHVEIEDK NPTHRLYRDL IHSGLAFGAE  480
RWLAILCRMC ERFACLMVTS SSTTRDLGGV IPSPDGKRSM MKLAQRMVNN FCASISTSNG  540
HRWTTLSGMN EVGVRVTVHK STDPGQPNGV VLSAATTIWL PISPQNVFNF FKDERTRGQW  600
DVLSNGNGVQ EVAHIANGSH PGNCISVLRA FNTSQNNMLI LQESCVDSSG ALVVYCPVDL  660
PAINIAMSGE DPSYIPLLPS GFTISPDGRP DHMQGGDVAS TSSSTHGSMA RLGSGSLITV  720
AFQILVSSLP SAKLNLESVT TVNNLIGSTV QQIKAALNCP SS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018849090.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2I4GYW10.0A0A2I4GYW1_JUGRE; homeobox-leucine zipper protein HDG11-like
STRINGXP_010099679.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]