PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans

Family

ERF

Protein Properties

Length: 229aa MW: 26207.4 Da PI: 5.243

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
WALNUT_00005579-RA	genome	JHU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	57.7	2.9e-18	92	142	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 y+GVr+++ +g+++AeIrd + + r++lg+f++ae Aa a+++a+ +++g WALNUT_00005579-RA 92 SYRGVRRRP-WGKYAAEIRDSTR---HgIRVWLGTFDSAEAAALAYDQAAFSMRG 142 69*****.******422...25***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	4.65E-19	91	149	No hit	No description
SuperFamily	SSF54171	8.5E-22	92	152	IPR016177	DNA-binding domain
SMART	SM00380	1.3E-36	92	156	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.3E-28	92	150	IPR001471	AP2/ERF domain
Pfam	PF00847	3.5E-13	92	142	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.431	92	150	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-10	93	104	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-10	116	132	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 229 aa Download sequence Send to blast
MESCYFDQYP SSEFSQESLS LDESFPWDKL LFHHSSLPFN LDDSEEMLLM DVIAKGSSTQ 60 TWETANSMQG VVKEEEVTSN DKEEANHKKE KSYRGVRRRP WGKYAAEIRD STRHGIRVWL 120 GTFDSAEAAA LAYDQAAFSM RGTLAVLNFT VEVVRESLQD MKDGNYEEGC SPVVALKRKH 180 SMRRKSMSRR SKGKEEMMRP QKVVVLEDLG AEYLEELLRL SPSQNSCPQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	8e-28	85	152	10	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018827139.1	1e-172	PREDICTED: ethylene-responsive transcription factor 1B-like isoform X1
Swissprot	A0A3Q7I5Y9	2e-73	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A2I4F661	1e-170	A0A2I4F661_JUGRE; ethylene-responsive transcription factor 1B-like isoform X1
STRING	POPTR_0005s24460.1	5e-79	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF311	33	199

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	9e-48	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]