PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Vradi07g13250.1
Organism
Vigna radiata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna
Family TCP
Protein Properties Length: 842aa    MW: 91739.1 Da    PI: 8.6429
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Vradi07g13250.1genomeSNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP1134.1e-35571671298
              TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec........eaesssssasnsss 87 
                       +++++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++t+ WLl+ +++ai+e+tgt++ +a ++         + ss ++++    
  Vradi07g13250.1 571 SPRRSSTKDRHTKVEGRGRRIRIPATCAARIFQLTRELGHKSDGETVRWLLEHSEQAIIEATGTGTVPAIAVsvggalkiPTTSSANQNK---- 660
                      5799************************************************************88888444333332211111111111.... PP

              TCP  88 gkaaksaaksk 98 
                      g++ +s++k+k
  Vradi07g13250.1 661 GEEGASNKKRK 671
                      11111111111 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF011541.4E-19291IPR013528Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
Gene3DG3DSA:3.40.47.101.3E-793256IPR016039Thiolase-like
CDDcd008272.19E-654358No hitNo description
SuperFamilySSF539011.34E-214162IPR016039Thiolase-like
TIGRFAMsTIGR018333.1E-15991439IPR010122Hydroxymethylglutaryl-CoA synthase, eukaryotic
PfamPF011545.6E-3592164IPR013528Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
PROSITE patternPS01226095110IPR000590Hydroxymethylglutaryl-coenzyme A synthase, active site
PfamPF085404.4E-110165439IPR013746Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain
SuperFamilySSF539015.76E-63165252IPR016039Thiolase-like
SuperFamilySSF539015.76E-63290437IPR016039Thiolase-like
PfamPF036341.3E-28576662IPR005333Transcription factor, TCP
PROSITE profilePS5136926.157577631IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008299Biological Processisoprenoid biosynthetic process
GO:0004421Molecular Functionhydroxymethylglutaryl-CoA synthase activity
Sequence ? help Back to Top
Protein Sequence    Length: 842 aa     Download sequence    Send to blast
MAKNVGILAI DIYFPPTCIQ QEVLEAHDGA SKGKYTIGLG QDCMAFCTEV EDVISMRTLL  60
LRTNSGIFSL TVVSSLLEKY KIDPKQIGRL EKYGNTDIEG VDSTNACYGG TAALFNCVNW  120
VESNSWDGRY GLVVCTDSAV YAEGPARPTG GAAAIAMLIG PDAPIAFESK LRGSHMAHAY  180
DFYKPNLASE YPVVDGKLSQ TCYLMALDSC YNLLSHKYEK LVGKQFSISD AEYFVFHSPY  240
NKLVQKSFAR LVFNDFLKNP SSVDAIAKEK LQPFATLSVD ESYQSRDLEK ASQQVAKPQF  300
DAKVQPTTLI PKQVGNMYTA SLYAAFISLI HNKHSTLDSK RVILFSYGSG LTSTMFSLQL  360
REGESPFSLS NIVKVMDVAG KLKSRHEFSP EKFVETMKLM ECRYGAKEFV TSKDTSLLSL  420
GTFYLTEVDS MYRRFYAKKM HFGVLATTPK KFPSAPSLDF TEANPTRKKK KNISKSLWIN  480
LPIQMSGMAS NQEEQDQDGG TTDLSTSDVD ADKALSKTTN LNGLHQHFQD KPIAFQVLPL  540
KNEPTDSDPD PDPNAPNPPP PPPTMHLPLK SPRRSSTKDR HTKVEGRGRR IRIPATCAAR  600
IFQLTRELGH KSDGETVRWL LEHSEQAIIE ATGTGTVPAI AVSVGGALKI PTTSSANQNK  660
GEEGASNKKR KRPSNSEFVD INDTVSQTSG LAPVQVPQGL VPVWAVSNPS MVVPANTFWM  720
IPQAATTRNP LGGVTGPSSH QPQIWALSPS VFNVAARPIS PLVTTRNIPE AWSVMAACSN  780
GSNSAAVSTS SVGARSSTNS SMAPSVPSSA TKTQTLRDFS LQIYDKQELQ FLGRSGPNAN  840
P*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2f82_A0.024391450HMG-CoA synthase
2f9a_A0.0243914503-Hydroxy-3-methylglutaryl coenzyme A synthase 1
2fa0_A0.024391450HMG-CoA synthase
2fa3_A0.024391450HMG-CoA synthase
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtThis enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Devoided of acetoacetyl-CoA thiolase (AACT) activity. Required for the development of both tapetosomes and elaioplasts in tapetal cells and for pollen viability during pollen tube elongation. {ECO:0000269|PubMed:20484369}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapVradi07g13250.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0150340.0AP015034.1 Vigna angularis var. angularis DNA, chromosome 1, almost complete sequence, cultivar: Shumari.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_014507032.10.0LOW QUALITY PROTEIN: hydroxymethylglutaryl-CoA synthase-like
SwissprotP548730.0HMCS_ARATH; Hydroxymethylglutaryl-CoA synthase
TrEMBLA0A1S3UM040.0A0A1S3UM04_VIGRR; 3-hydroxy-3-methylglutaryl coenzyme A synthase
STRINGXP_007155571.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF364322
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G45680.18e-69TCP family protein
Publications ? help Back to Top
  1. Lange BM,Ghassemian M
    Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
    Plant Mol. Biol., 2003. 51(6): p. 925-48
    [PMID:12777052]
  2. Nagegowda DA,Bach TJ,Chye ML
    Brassica juncea 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase 1: expression and characterization of recombinant wild-type and mutant enzymes.
    Biochem. J., 2004. 383(Pt. 3): p. 517-27
    [PMID:15233626]
  3. Bach TJ, et al.
    Aspects related to mevalonate biosynthesis in plants.
    Lipids, 1991. 26(8): p. 637-48
    [PMID:1685759]
  4. Ishiguro S, et al.
    The Arabidopsis FLAKY POLLEN1 gene encodes a 3-hydroxy-3-methylglutaryl-coenzyme A synthase required for development of tapetum-specific organelles and fertility of pollen grains.
    Plant Cell Physiol., 2010. 51(6): p. 896-911
    [PMID:20484369]
  5. Liao P, et al.
    Past achievements, current status and future perspectives of studies on 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) in the mevalonate (MVA) pathway.
    Plant Cell Rep., 2014. 33(7): p. 1005-22
    [PMID:24682521]
  6. Weber T,Bach TJ
    Conversion of acetyl-coenzyme A into 3-hydroxy-3-methylglutaryl-coenzyme A in radish seedlings. Evidence of a single monomeric protein catalyzing a FeII/quinone-stimulated double condensation reaction.
    Biochim. Biophys. Acta, 1994. 1211(1): p. 85-96
    [PMID:8123686]
  7. Montamat F,Guilloton M,Karst F,Delrot S
    Isolation and characterization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl-coenzyme A synthase.
    Gene, 1995. 167(1-2): p. 197-201
    [PMID:8566777]