PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna

Family

MIKC_MADS

Protein Properties

Length: 196aa MW: 22972.1 Da PI: 8.0559

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Vradi07g13200.1	genome	SNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	95.8	1.8e-30	9	59	1	51
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51 krien++ rqvtfskRrng+lKKA+ELSvLCdaeva+iifs++g+lye+ss Vradi07g13200.1 9 KRIENETSRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSTRGRLYEFSS 59 79***********************************************96 PP
2	K-box	61.6	3.1e-21	92	160	14	82
K-box 14 aeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqk 82 ++ l+ + + ie L+++ R+llG++L+++sl eL+qLe+qLe+sl+kiR++Kn++++eqie+l++ Vradi07g13200.1 92 TQILKDGGMSMTETIEHLENSRRKLLGDELDTCSLDELRQLENQLERSLEKIRARKNQMFTEQIEKLKE 160 5556666668999****************************************************9975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	1.5E-39	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	31.917	1	61	IPR002100	Transcription factor, MADS-box
CDD	cd00265	1.44E-35	3	76	No hit	No description
PROSITE pattern	PS00350	0	3	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.3E-31	3	23	IPR002100	Transcription factor, MADS-box
SuperFamily	SSF55455	5.36E-30	3	77	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	1.7E-26	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.3E-31	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.3E-31	38	59	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS51297	13.278	92	189	IPR002487	Transcription factor, K-box
Pfam	PF01486	1.4E-19	93	161	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 196 aa Download sequence Send to blast
MVRGKTQMKR IENETSRQVT FSKRRNGLLK KAFELSVLCD AEVALIIFST RGRLYEFSSS 60 TSRCSSINKT VERYQKKIKD FGDSHKGIHE NTQILKDGGM SMTETIEHLE NSRRKLLGDE 120 LDTCSLDELR QLENQLERSL EKIRARKNQM FTEQIEKLKE EYLIERGRYL SDEDLEVVRE 180 KKEEEVETEL FIGRR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1tqe_P	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
1tqe_Q	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
1tqe_R	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
1tqe_S	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
5f28_A	1e-17	1	60	1	60	MEF2C
5f28_B	1e-17	1	60	1	60	MEF2C
5f28_C	1e-17	1	60	1	60	MEF2C
5f28_D	1e-17	1	60	1	60	MEF2C
6byy_A	1e-17	1	95	1	85	MEF2 CHIMERA
6byy_B	1e-17	1	95	1	85	MEF2 CHIMERA
6byy_C	1e-17	1	95	1	85	MEF2 CHIMERA
6byy_D	1e-17	1	95	1	85	MEF2 CHIMERA
6c9l_A	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
6c9l_B	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
6c9l_C	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
6c9l_D	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
6c9l_E	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
6c9l_F	8e-18	1	95	1	85	Myocyte-specific enhancer factor 2B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner. {ECO:0000269\|PubMed:16778081}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Vradi07g13200.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Maintained at very low levels by the polycomb-group (PcG) proteins MSI1, CLF, and EMF2 via histone methylation (H3K27me3). Derepressed upon cold treatment (vernalization). {ECO:0000269\|PubMed:16778081}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_014507710.1	1e-117	agamous-like MADS-box protein AGL14 isoform X2
Swissprot	O82743	3e-66	AGL19_ARATH; Agamous-like MADS-box protein AGL19
TrEMBL	A0A0S3R649	1e-116	A0A0S3R649_PHAAN; Uncharacterized protein
STRING	GLYMA05G03660.8	1e-101	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF666	30	102

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G22950.1	2e-68	AGAMOUS-like 19

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Suter L,Rüegg M,Zemp N,Hennig L,Widmer A Gene regulatory variation mediates flowering responses to vernalization along an altitudinal gradient in Arabidopsis. Plant Physiol., 2014. 166(4): p. 1928-42 [PMID:25339407]