PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna

Family

AP2

Protein Properties

Length: 647aa MW: 72365 Da PI: 6.5888

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Vang11g04900.1	genome	SNU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	25.7	2.9e-08	315	384	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pse.ng........kr.....krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++gr++A+++d ++ g k+ +f ++ +e+Aa+a++ a++k++g Vang11g04900.1 315 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqsrkgrqgKKgvifpHHFIFRGYDMEEKAARAYDLAALKYWG 384 78*****************988884446668888334668999*********************98 PP
2	AP2	28.8	3.1e-09	416	455	13	55
AP2 13 grWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 rW A+I + +k +lg+f t eeAa+a++ a+ k++g Vang11g04900.1 416 RRWQARIGRVA---GNKDLYLGTFSTQEEAAEAYDIAAIKFRG 455 35666655531...36************************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	5.61E-16	315	392	No hit	No description
Pfam	PF00847	4.8E-5	315	384	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.03E-10	315	394	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	1.1E-9	316	393	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	16.397	316	463	IPR001471	AP2/ERF domain
SMART	SM00380	1.1E-17	316	398	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	317	328	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	2.1E-13	415	463	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	7.85E-13	415	464	IPR016177	DNA-binding domain
SMART	SM00380	2.1E-20	417	469	IPR001471	AP2/ERF domain
CDD	cd00018	4.57E-19	417	465	No hit	No description
PRINTS	PR00367	4.9E-6	445	465	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 647 aa Download sequence Send to blast
MKSMENDDSV DLNNQNNWLG FSLSPQMNVG VASHPQPSSA ADVVPTSFYH TAPLNNYGFY 60 YGLEAENVGL YSALPIMPLK SDGSLYGMEA LSRSQTQAMA TTSTPKLENF FGGEAMGTPH 120 YECSVTETIP LSLDSVFYNQ SSRRDPNNQT FQNHVQHITT QQQHQQDLQA QHLSYYSTLR 180 NHDMMLEGSK QSQTSDSNLQ LPNMGDDGVP APGLKSWGVR NFQTSHAQDS KLIVPVEENG 240 GESGSIGSMA YGDLQSLSLS MSPSSQSSCV TSSHRTSPAV IDSVAMDTKK RGPEKVDQKQ 300 IIHRKSIDTF GQRTSQYRGV TRHRWTGRYE AHLWDNSCKK EGQSRKGRQG KKGVIFPHHF 360 IFRGYDMEEK AARAYDLAAL KYWGPSTHIN FPLENYQNEL EEMKNMTRQE YVAHLRRWQA 420 RIGRVAGNKD LYLGTFSTQE EAAEAYDIAA IKFRGVNAVT NFDITRYDVE KIMASSNLLS 480 SELARRNRET DSGTQYIDHN HKSSAYDDTQ EAILMQKSCE SQNEQWKMAP YQSSQQLDQN 540 PPRTESDRTN QSFSVALDNM FHQEVEESRK VRTHVSNPSS LATSLNSSRE GSPDRTSLPM 600 LSGMPSTASK LLSTNPNNVN SWDPSPHLRP ALSLPQMPVF AAWTDA*

Sequence ? help Back to Top

Protein Sequence Length: 647 aa Download sequence Send to blast

MKSMENDDSV DLNNQNNWLG FSLSPQMNVG VASHPQPSSA ADVVPTSFYH TAPLNNYGFY  60
YGLEAENVGL YSALPIMPLK SDGSLYGMEA LSRSQTQAMA TTSTPKLENF FGGEAMGTPH  120
YECSVTETIP LSLDSVFYNQ SSRRDPNNQT FQNHVQHITT QQQHQQDLQA QHLSYYSTLR  180
NHDMMLEGSK QSQTSDSNLQ LPNMGDDGVP APGLKSWGVR NFQTSHAQDS KLIVPVEENG  240
GESGSIGSMA YGDLQSLSLS MSPSSQSSCV TSSHRTSPAV IDSVAMDTKK RGPEKVDQKQ  300
IIHRKSIDTF GQRTSQYRGV TRHRWTGRYE AHLWDNSCKK EGQSRKGRQG KKGVIFPHHF  360
IFRGYDMEEK AARAYDLAAL KYWGPSTHIN FPLENYQNEL EEMKNMTRQE YVAHLRRWQA  420
RIGRVAGNKD LYLGTFSTQE EAAEAYDIAA IKFRGVNAVT NFDITRYDVE KIMASSNLLS  480
SELARRNRET DSGTQYIDHN HKSSAYDDTQ EAILMQKSCE SQNEQWKMAP YQSSQQLDQN  540
PPRTESDRTN QSFSVALDNM FHQEVEESRK VRTHVSNPSS LATSLNSSRE GSPDRTSLPM  600
LSGMPSTASK LLSTNPNNVN SWDPSPHLRP ALSLPQMPVF AAWTDA*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269\|PubMed:10528263, ECO:0000269\|PubMed:10639184, ECO:0000269\|PubMed:10948255, ECO:0000269\|PubMed:11041883, ECO:0000269\|PubMed:12183381, ECO:0000269\|PubMed:12271029, ECO:0000269\|PubMed:12655002, ECO:0000269\|PubMed:8742706, ECO:0000269\|PubMed:8742707, ECO:0000269\|PubMed:9001406, ECO:0000269\|PubMed:9093862, ECO:0000269\|PubMed:9118807}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Vang11g04900.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AP015034	0.0	AP015034.1 Vigna angularis var. angularis DNA, chromosome 1, almost complete sequence, cultivar: Shumari.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027920761.1	0.0	AP2-like ethylene-responsive transcription factor ANT isoform X1
Swissprot	Q38914	1e-132	ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBL	A0A4D6KU15	0.0	A0A4D6KU15_VIGUN; AP2-like factor
STRING	XP_007155799.1	0.0	(Phaseolus vulgaris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF916	34	114

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G37750.1	4e-93	AP2 family protein

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Horstman A,Willemsen V,Boutilier K,Heidstra R AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks. Trends Plant Sci., 2014. 19(3): p. 146-57 [PMID:24280109] Li C, et al. Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis. PLoS ONE, 2014. 9(4): p. e94830 [PMID:24756087] Wynn AN,Seaman AA,Jones AL,Franks RG Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development. Front Plant Sci, 2014. 5: p. 130 [PMID:24778638] Randall RS, et al. AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins. Biol Open, 2015. 4(10): p. 1229-36 [PMID:26340943] Meng LS,Wang ZB,Yao SQ,Liu A The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis. J. Cell. Sci., 2015. 128(21): p. 3922-32 [PMID:26395398] Yang K, et al. Genome sequencing of adzuki bean (Vigna angularis) provides insight into high starch and low fat accumulation and domestication. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(43): p. 13213-8 [PMID:26460024] Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis. Plant Physiol., 2016. 170(1): p. 283-93 [PMID:26537561] Krizek BA, et al. RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways. Plant Physiol., 2016. 171(3): p. 2069-84 [PMID:27208279] Han H,Krizek BA AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels. Plant Mol. Biol., 2016. 92(4-5): p. 597-612 [PMID:27605095] Karpinska B,Alomrani SO,Foyer CH Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018. [PMID:28808105] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]