PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Traes_6AS_DA75BB1FD.1
Common NameWRKY80
Organism
Triticum aestivum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
Family WRKY
Protein Properties Length: 300aa    MW: 32618.4 Da    PI: 8.3712
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Traes_6AS_DA75BB1FD.1genomeIWGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY96.32.1e-30192251159
                            ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
                   WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                            ++Dgy+WrKYGqK+ k++++pr+Y+rC++a gCpvkkkv+rsaed+++++ tYegeHnh+
  Traes_6AS_DA75BB1FD.1 192 VKDGYQWRKYGQKVTKDNPCPRAYFRCSFApGCPVKKKVQRSAEDKTILVATYEGEHNHT 251
                            58***************************99****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5081126.991187253IPR003657WRKY domain
Gene3DG3DSA:2.20.25.806.4E-30191253IPR003657WRKY domain
SuperFamilySSF1182903.4E-26191253IPR003657WRKY domain
SMARTSM007741.2E-35192252IPR003657WRKY domain
PfamPF031062.1E-25193250IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0002237Biological Processresponse to molecule of bacterial origin
GO:0002238Biological Processresponse to molecule of fungal origin
GO:0009409Biological Processresponse to cold
GO:0009414Biological Processresponse to water deprivation
GO:0009611Biological Processresponse to wounding
GO:0009623Biological Processresponse to parasitic fungus
GO:0009651Biological Processresponse to salt stress
GO:0009685Biological Processgibberellin metabolic process
GO:0009723Biological Processresponse to ethylene
GO:0009737Biological Processresponse to abscisic acid
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0010200Biological Processresponse to chitin
GO:0031347Biological Processregulation of defense response
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:1990841Molecular Functionpromoter-specific chromatin binding
Sequence ? help Back to Top
Protein Sequence    Length: 300 aa     Download sequence    Send to blast
MDPWVSSQPS LSLDLHVGLP PMGHHQAAPM VALAKPKVLV EENFMQLKKD PEVAVLESEL  60
QRVSEENRRL GEMLREVASK YEALQGQFTD MVTAGAHAGG NNSHYNNQPS SASEGGSVSP  120
SRKRKSEESL GTPPRPSQHQ QQHYAGGLAY AAAPDQAECT SGEPCKRIRE ECKPVVSKRY  180
VHADPSDLSL VVKDGYQWRK YGQKVTKDNP CPRAYFRCSF APGCPVKKKV QRSAEDKTIL  240
VATYEGEHNH TQPPPSQPQQ QNDGSGAGKN AGKPPQAPTA TPHHPQQQHK QEAAAAAVSG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A4e-211912541375WRKY transcription factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1120125SRKRKS
Functional Description ? help Back to Top
Source Description
UniProtTranscription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:18175928, PubMed:15047897, PubMed:16623886). Represses specifically gibberellic acid (GA)-induced promoters in aleurone cells, probably by interfering with GAM1 (PubMed:15047897, PubMed:16623886, PubMed:19199048). Regulates, probably indirectly, the activation of defense-related genes such as GF14E during defense response (PubMed:18175928, PubMed:26851365, PubMed:26467468). Modulates plant innate immunity against X.oryzae pv. oryzae (Xoo) (PubMed:21961049). Confers resistance to the virulent bacterial pathogen Xoo 13751, probably via the regulation of NPR1 and PR1b defense signaling pathways (PubMed:16919842). {ECO:0000269|PubMed:15047897, ECO:0000269|PubMed:16623886, ECO:0000269|PubMed:16919842, ECO:0000269|PubMed:18175928, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:21961049, ECO:0000269|PubMed:26467468, ECO:0000269|PubMed:26851365}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by biotic elicitors (e.g. fungal chitin oligosaccharide and fungal cerebroside elicitors) and pathogen infection (e.g. the compatible pathogenic fungus M.grisea race 007, M. grisea crabgrass BR29) (PubMed:18175928, PubMed:19772648, PubMed:23462973). Accumulates in response to M.oryzae (PubMed:21726398). Triggered by defense signaling molecules, such as salicylic acid (SA), methyl jasmonate (MeJA), 1-aminocyclo-propane-1-carboxylic acid (ACC), wounding and pathogen infection (e.g. X.oryzae) (PubMed:16919842). Repressed by gibberellic acid (GA) (at protein level) (PubMed:15047897, PubMed:19199048). Induced by abscisic acid (ABA) in aleurone cells, roots and leaves (PubMed:15618416, PubMed:16623886). Accumulates in response to uniconazole, a GA biosynthesis inhibitor (PubMed:16623886). Triggered strongly by cold in leaves, stems and developing spikes, but moderately by drought and salt stresses (PubMed:14645724, PubMed:23495849). {ECO:0000269|PubMed:14645724, ECO:0000269|PubMed:15047897, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:16623886, ECO:0000269|PubMed:16919842, ECO:0000269|PubMed:18175928, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:19772648, ECO:0000269|PubMed:21726398, ECO:0000269|PubMed:23462973, ECO:0000269|PubMed:23495849}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankJX6790790.0JX679079.1 Triticum aestivum WRKY80 transcription factor (WRKY80) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020192814.10.0WRKY transcription factor WRKY71-like
SwissprotQ6QHD11e-124WRK71_ORYSJ; WRKY transcription factor WRKY71
TrEMBLA0A1S5S7I50.0A0A1S5S7I5_TRITU; WRKY-like protein
TrEMBLK7WPK50.0K7WPK5_WHEAT; WRKY80 transcription factor
STRINGTraes_6AS_DA75BB1FD.10.0(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP182238103
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G80840.19e-49WRKY DNA-binding protein 40
Publications ? help Back to Top
  1. Rabbani MA, et al.
    Monitoring expression profiles of rice genes under cold, drought, and high-salinity stresses and abscisic acid application using cDNA microarray and RNA gel-blot analyses.
    Plant Physiol., 2003. 133(4): p. 1755-67
    [PMID:14645724]
  2. Zhang Y,Wang L
    The WRKY transcription factor superfamily: its origin in eukaryotes and expansion in plants.
    BMC Evol. Biol., 2005. 5: p. 1
    [PMID:15629062]
  3. Wu KL,Guo ZJ,Wang HH,Li J
    The WRKY family of transcription factors in rice and Arabidopsis and their origins.
    DNA Res., 2005. 12(1): p. 9-26
    [PMID:16106749]
  4. Xie Z, et al.
    Interactions of two abscisic-acid induced WRKY genes in repressing gibberellin signaling in aleurone cells.
    Plant J., 2006. 46(2): p. 231-42
    [PMID:16623886]
  5. Zou X,Neuman D,Shen QJ
    Interactions of two transcriptional repressors and two transcriptional activators in modulating gibberellin signaling in aleurone cells.
    Plant Physiol., 2008. 148(1): p. 176-86
    [PMID:18621977]
  6. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  7. Berri S, et al.
    Characterization of WRKY co-regulatory networks in rice and Arabidopsis.
    BMC Plant Biol., 2009. 9: p. 120
    [PMID:19772648]
  8. Delteil A, et al.
    Building a mutant resource for the study of disease resistance in rice reveals the pivotal role of several genes involved in defence.
    Mol. Plant Pathol., 2012. 13(1): p. 72-82
    [PMID:21726398]
  9. Peng Y,Bartley LE,Canlas P,Ronald PC
    OsWRKY IIa Transcription Factors Modulate Rice Innate Immunity.
    Rice (N Y), 2010. 3(1): p. 36-42
    [PMID:21961049]
  10. Chujo T, et al.
    OsWRKY28, a PAMP-responsive transrepressor, negatively regulates innate immune responses in rice against rice blast fungus.
    Plant Mol. Biol., 2013. 82(1-2): p. 23-37
    [PMID:23462973]
  11. Kovalchuk N, et al.
    Optimization of TaDREB3 gene expression in transgenic barley using cold-inducible promoters.
    Plant Biotechnol. J., 2013. 11(6): p. 659-70
    [PMID:23495849]
  12. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  13. Liu Q, et al.
    OsGF14b Positively Regulates Panicle Blast Resistance but Negatively Regulates Leaf Blast Resistance in Rice.
    Mol. Plant Microbe Interact., 2016. 29(1): p. 46-56
    [PMID:26467468]
  14. Liu Q, et al.
    OsGF14e positively regulates panicle blast resistance in rice.
    Biochem. Biophys. Res. Commun., 2016. 471(1): p. 247-52
    [PMID:26851365]