PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum

Family

MYB

Protein Properties

Length: 324aa MW: 35537.8 Da PI: 6.42

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Traes_1AS_36AF74187.2	genome	IWGSC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	63.8	3.4e-20	47	94	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+WT+eEd llvd++ ++G g+W++ ar+ g++Rt+k+c++rw++yl Traes_1AS_36AF74187.2 47 RGPWTAEEDMLLVDYISKHGEGRWNSLARCAGLRRTGKSCRLRWLNYL 94 89********************************************97 PP
2	Myb_DNA-binding	53.4	5.8e-17	100	143	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 rg+ T+eE++l++d++ ++G++ W++Ia++++ gRt++++k++w++ Traes_1AS_36AF74187.2 100 RGNITPEEQLLILDLHSRWGNR-WSKIAQRLP-GRTDNEVKNYWRT 143 7999****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	23.392	42	98	IPR017930	Myb domain
SuperFamily	SSF46689	4.12E-32	44	141	IPR009057	Homeodomain-like
SMART	SM00717	4.8E-17	46	96	IPR001005	SANT/Myb domain
Pfam	PF00249	1.2E-17	47	94	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	4.0E-24	48	101	IPR009057	Homeodomain-like
CDD	cd00167	8.53E-14	49	94	No hit	No description
PROSITE profile	PS51294	18.815	99	149	IPR017930	Myb domain
SMART	SM00717	7.1E-15	99	147	IPR001005	SANT/Myb domain
Pfam	PF00249	2.1E-15	100	143	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	3.2E-23	102	148	IPR009057	Homeodomain-like
CDD	cd00167	5.97E-12	104	143	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 324 aa Download sequence Send to blast
MDMDKEYYKA CMGMEALPMS PAGFSAVTTE AAMAVATASE DEGDLKRGPW TAEEDMLLVD 60 YISKHGEGRW NSLARCAGLR RTGKSCRLRW LNYLRPDVRR GNITPEEQLL ILDLHSRWGN 120 RWSKIAQRLP GRTDNEVKNY WRTRVQKHAK QLHCDVNSDR FRDVVRQVWM PRLLERIQAE 180 SSSSSAAAAA GVGVPALTRA MSSPAGASQY HCFDHASSGG PSRKVAVTMS PDTSSTLRSS 240 LSPAETSHGA HFPAWGAATA TANVDGSMMQ CAGREGGAIG GDQYVIHGDS LSGSWSELLA 300 ATDIPDFEFG NFDDNLWSLE DIYC

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	3e-26	44	141	24	120	MYB TRANSFORMING PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in abiotic stress responses. Plays a regulatory role in tolerance to salt, cold, and drought stresses. Regulates positively the expression of genes involved in proline synthesis and transport, and genes involved in reactive oxygen species (ROS) scavenging such as peroxidase, superoxide dismutase and catalase during salt stress. Transactivates stress-related genes, including LEA3, RAB16A and DREB2A during salt stress. {ECO:0000269\|PubMed:22301384}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by salt, cold and osmotic stresses, and abscisic acid (ABA). Down-regulated by salicylic acid (SA). {ECO:0000269\|PubMed:22301384}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EF587267	0.0	EF587267.1 Triticum aestivum R2R3 Myb-like protein (PIMP1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020164818.1	0.0	transcription factor MYB30-like
Swissprot	Q10MB4	7e-87	MYB2_ORYSJ; Transcription factor MYB2
TrEMBL	A0A3B5XV54	0.0	A0A3B5XV54_WHEAT; Uncharacterized protein
TrEMBL	A0A446IM09	0.0	A0A446IM09_TRITD; Uncharacterized protein
STRING	Traes_1AS_36AF74187.2	0.0	(Triticum aestivum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP198	38	330

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G48000.1	7e-78	myb domain protein 112

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Yang A,Dai X,Zhang WH A R2R3-type MYB gene, OsMYB2, is involved in salt, cold, and dehydration tolerance in rice. J. Exp. Bot., 2012. 63(7): p. 2541-56 [PMID:22301384] Brenchley R, et al. Analysis of the bread wheat genome using whole-genome shotgun sequencing. Nature, 2012. 491(7426): p. 705-10 [PMID:23192148] Chen X, et al. The NAC family transcription factor OsNAP confers abiotic stress response through the ABA pathway. Plant Cell Physiol., 2014. 55(3): p. 604-19 [PMID:24399239] Lv Y, et al. New insights into the genetic basis of natural chilling and cold shock tolerance in rice by genome-wide association analysis. Plant Cell Environ., 2016. 39(3): p. 556-70 [PMID:26381647] Hong Y,Zhang H,Huang L,Li D,Song F Overexpression of a Stress-Responsive NAC Transcription Factor Gene ONAC022 Improves Drought and Salt Tolerance in Rice. Front Plant Sci, 2016. 7: p. 4 [PMID:26834774]